Jack Kruse认为，光（特别是紫外光和生物光子）在生命的起源和进化中扮演了远超传统生物化学所理解的关键角色，光直接影响基因表达、能量转换和复杂性的构建。 他批评了传统生物化学和进化论对光的忽略，并认为这种忽略导致了对生命本质的误解。

POMC (Proopiomelanocortin) 与紫外光：

• POMC 是一种在哺乳动物中非常重要的基因。
• 紫外光是翻译（表达）POMC 基因的关键刺激因素。
• 这种紫外光不仅来自太阳，对于早期动物而言，还来自其自身产生的超弱生物光子 (ultra weak biophotons)，其光谱范围通常在200-400纳米（紫外光谱）。

线粒体内膜与能量转换的光学特性：

• 哺乳动物的瘦素-黑皮质素通路 (leptin-melanocortin pathway) 和血红蛋白与线粒体内膜的故事都与光有关。
• 线粒体内膜上发生 NAD 到氧气的电子传递，涉及-400到+400毫伏的电位差。
• 细胞色素I (Cytochrome I) 的吸收光谱在340纳米（紫外区），发射光谱在蓝光区（黄素范围）。这解释了为什么第二个细胞色素是蓝光吸收体。
• 细胞色素I 还会产生线粒体中最强的超氧化物脉冲。自由基是未配对电子，这意味着它们都有吸收和发射光谱。

对传统生物化学的批评与雷佩特Ray Peat的交流：

• Kruse认为生物化学领域尚未充分理解吸收和发射光谱的重要性。
• 他曾与著名的生物化学家 雷佩特Ray Peat 交流过这些观点，但雷佩特当时似乎并未完全接受。
• Kruse的核心论点是：任何具有吸收和发射光谱的物质，都意味着光必然是其故事的一部分。

Albert Szent-Györgyi 的远见与 Robert O. Becker 的证明：

• Kruse追溯到 Albert Szent-Györgyi（因克雷布斯循环研究的“错误”而获得诺贝尔奖，这本身就是一种讽刺的说法，暗示主流观点可能存在偏差）在1941年布达佩斯会议上的观点：DNA 唯一编码的是蛋白质，而蛋白质具有类似半导体的电子结构。
• 当时听众席上的 Robert O. Becker 在不到二十年的时间里证明了Szent-Györgyi 的观点是正确的（暗示生物体内的电磁现象和半导体特性）。

哺乳动物从缺氧到有氧的进化与紫外光的选择：

• 当Kruse向雷佩特t解释这些时，他指出雷佩特Ray Peat的理解基于传统的“盒子车厢”式（指模块化、线性）的生化途径，而忽略了量子生物学层面。
• 哺乳动物从缺氧环境进化到依赖氧气的TCA循环（三羧酸循环）。
• 在线粒体层面，这意味着在量子生物学层面（而非达尔文的自然选择层面）制造并选择了那些发射光谱在紫外范围内的化学物质。

能量、复杂性与 E=mc²：

• 如果这种“开关”（指对紫外光的利用）发生，生物体就获得了构建更大、更复杂结构的能量潜力。
• 这与 E=mc² 的原理类似：能量和质量是等同的。拥有更多能量就能构建更多“质量”（即复杂性）。
• 引用 Ilya Prigogine 的理论（1977年诺贝尔奖）：细胞是一个量子单元，设计用来将光泵入其中。通过光电转换的电阻 (photoelectrical resistance) 来构建复杂性。细胞内的电阻减慢光速，细胞内的物质捕获这些能量，从而构建复杂性。
• 这与婴儿在母体内发育的原理是分形相似的。

对主流生物化学和进化生物学的再次批评：

• Kruse认为，当人们用这种“光”的视角重新审视生物化学（如Lehninger生物化学教材）时，会发现传统教材完全忽略了吸收和发射光谱。
• 他认为自己之所以让进化生物学家和生物化学家感到“头痛”，是因为他不断指出这些被遗忘的关键特征。
• 主流科学界虽然知道GOE（大氧化事件）、寒武纪大爆发以及达尔文理论与寒武纪大爆发的不匹配之处，但由于“中心法则”的束缚，以及对科研经费（NIH、DARPA）的依赖，没有人愿意质疑。

播客的目的：

• Kruse强调，目的不是讨论中心化科学如何偏离轨道，而是向人们讲述生命的故事（暗示一个更接近真相、包含光的重要性的版本）。

总结来说，Kruse 试图构建一个基于量子生物学和光物理学的生命叙事，挑战了传统生物化学和进化论中以化学反应和基因为核心的解释框架。他认为，紫外光和生物光子是驱动生命进化、基因表达和能量转换的核心要素，而对这些光学现象的忽略导致了对生命本质的片面理解。他暗示这种颠覆性的观点因不符合主流科学范式和科研资助体系而受到压制。

Edit:2025.09.26

or palm seed. What is palm seed?

Proopopio melano cortin. It's a it's a

gene in mammals that that is really what

we specialize in. And it turns out what

translates palm seed from our DNA? UV

lights the stimulus. Where does that

light come from? Most people think that

it's from uh the sun. I'm going to tell

you in the original animals that first

come out, it's not only from the sun,

but it's also from the ultra weak

biopotons that they make, which tends to

be in the ultra weak um spectrum, which

is 200 to 400. How do we know that?

Because everything that is about a

mammal, which is the leptin melanoordin

pathway, and then this hemoglobin story

with the inner mitochondrial membrane

becomes sculpted. That's where you have

NAD to oxygen. What's the the the change

there? -400 to positive400 volts. But

what's the other thing? What's the

emission and absorption spectra of

cytochrome 1? Turns out it absorbs at

340 and it emits in the blue range, in

the flavven range. That's why the second

cytochrome is a blue absorber. It also

turns out that it makes the most super

oxide pulse in all of the mitochondria,

which what are free radicals? Remember,

they're unpaired electrons. What does

that mean? It means they all have

absorption emission spectra. So the

other problem in biochemistry we haven't

got to but I did sit down with a famous

biochemist probably 10 or 15 years ago

that you probably heard of Ray Pete and

I tried to tell him this story and his

eyes were glazed over when he told me

all the things he said. I said Ray I

said do you understand that anything

that has an absorption and emission

spectrum means that light has to be part

of the story? And I told him how old the

story went. I said do you know who came

up with this idea originally? said it

was um guy who also won a Nobel Prize

for being wrong about the Kreb cycle

which was Albert St. Georgie and he said

the most interesting thing at a meeting

in 1941 in Budapest. He said the only

thing that DNA codes for is proteins and

he goes it's really funny when you look

at a protein they have an electronic

structure that mimics a semiconductor.

Do you know who is sitting in the

audience that day? Robert Obecker

literally within less than two decades

he proves that Albert St. Georgie is

correct. Okay. and he def beyond a

shadow of a doubt. So when I gave the

story to Ray, I said, “Ray, all the

things that you believe are based on

this paradigm of you learning about all

these box cars, but as you said, Nick,

in the beginning of this podcast, you're

like, Jack, it's not clear to me how the

two domains of life came together, which

is now you're asking me the next

question, which is beautiful because I

know you're understanding what I'm

saying now. So let's talk about what

happened to these mammals.” Turn out

these mammals went from being hypoxic to

TCA masters with oxygen. And what did

that mean at the mitochondrial level?

That means they made chemicals and

selected for chemicals at a quantum

biologic level, not at Darwin's level

that had emission spectras that were all

in the UV range. And now if the switch

happens, if the switch happens, you now

have the energetic potential to build

more and bigger complexity. You got it?

And that's exactly what the story of E=

MC² is. You know, I don't have to teach

you about that because you know energy

and mass and Einstein's equation are the

same. So the thing is if you're able to

have more energy in the system, which is

what Pigene's theorem is, he won the

Nobel Prize in 77. Basically, a a cell

is a quantum uh cell that's designed to

pump light into it. And what do we do

through electrical resistance? Photo

electrical resistance. That's how you

build the complexity. So, what are you

doing? The electrical resistance of

things in a cell slows the light down.

Those things harvest the power and then

we build the complexity from that. It's

no different than the story I told you

about what happens to a baby when it's

inside its mother. Okay? It's exact same

story. It's another fractal of the

story. And when you see it for yourself,

you start to look at biochemistry. You

start opening up your Lener biochemistry

and go, “Jesus Christ, I never learned

anything about absorption and emission

spectras.” And this is the reason why,

Nick, I'm such a pain in the ass for

guys like you that are in evolutionary

biology and biochemistry because I keep

pointing out these key features that

you're forgetting. And you guys know a

lot of the stuff I know. You know about

the GOE. You know about the Camrian

explosion. you know about Darwin and how

the story doesn't marry up to the

Cambridge explosion, but because it's

central dogma, nobody wants to question

it. Why? Because if you're a PhD, you'll

never get any money from the NIH or from

DARPA or for anybody else. And I

understand that. But remember, we're

doing this podcast not to talk about how

centralized science went off the rails.

We're actually trying to teach people

the story of life.

Edit:2025.09.26

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