Semtex :
我对生物黑客的兴趣由来已久，始于我对优化自身生物机能的追求，包括身体和精神层面。我始终认为，人类的一切行为都是为了从一种状态过渡到更好的状态，即使是刻意的痛苦，例如锻炼，也是为了提升自我。20年前，我开始尝试通过各种方法来优化我的大脑功能，当时可用的补剂有限。后来，由于患病导致神经疼痛，我开始关注勃起功能的改善。在研究过程中，我发现一氧化氮是勃起功能的关键信号分子，开始测试各种提高一氧化氮水平的补剂和组合，使用唾液测试条来量化其效果。
我的研究持续了三年，期间我测试了超过1000种化合物，严格控制饮食和生活习惯，以确保测试结果的准确性。 我的研究结果表明，钠和水分摄入对健身泵感至关重要。即使服用L-瓜氨酸或甘油等补充剂，如果钠和水分不足，也无法获得最佳效果。我发现，硝酸盐是提高一氧化氮水平的有效方法，但其吸收速度较慢，例如芝麻菜需要1小时，甜菜根需要2-3小时。而使用硝酸钠等补剂可以更快地提高硝酸盐水平，并同时补充钠。
除了补充剂，睡眠、阳光照射和抗氧化剂等因素也对一氧化氮的产生有重要影响。睡眠不足会影响内皮细胞的功能，阳光照射可以促进一氧化氮的产生，而抗氧化剂可以减少活性氧的产生，从而保护一氧化氮。
在补剂方面，N-乙酰半胱氨酸（NAC）可以提高一氧化氮水平，但也可能导致多巴胺钝化，因此需要谨慎使用。此外，亚甲蓝可能会抑制可溶性鸟苷酸环化酶，从而降低一氧化氮的效果。
在饮食方面，芝麻菜是提高一氧化氮水平最有效且方便的食物，其次是甜菜根和其他绿叶蔬菜。芝麻菜中含有少量苦味，但其高硝酸盐含量使其成为提高一氧化氮水平的理想选择。烹调可能会降低芝麻菜中的硝酸盐含量，但程度有限。芝麻菜与西地那非（伟哥）联合使用可以增强勃起效果。
碳水化合物对一氧化氮的产生也至关重要，低碳水饮食可能会降低一氧化氮水平。 在勃起功能障碍的治疗方面，我发现小檗碱可以长期抑制PDE5酶的表达，从而提高一氧化氮水平。
心理因素也对勃起功能有重要影响，压力、焦虑等负面情绪可能会导致勃起功能障碍。因此，保持良好的心理状态，例如进行体育锻炼、户外活动和社交等，对改善勃起功能至关重要。
我对生物黑客的兴趣由来已久，源于一种本能的渴望：优化自身生物机能，涵盖身心两方面。我坚信，人类所有行为的最终目的都是为了追求更好的状态，即使是刻意的痛苦，例如高强度训练，也是为了自我提升。
二十年前，我就开始探索提升大脑功能的方法，但当时可选择的补剂非常有限。后来，一场疾病导致我出现神经性疼痛，这促使我开始关注勃起功能的改善。深入研究后，我发现一氧化氮是勃起功能的关键信号分子，于是开始了对各种提升一氧化氮水平的补剂和组合的研究，并利用唾液测试条来量化实验结果。这项研究持续了三年，期间我测试了超过一千种化合物，严格控制饮食和生活习惯，力求确保数据的准确性。
钠和水分是健身泵感的重要因素。 我的研究结果表明，即使服用L-瓜氨酸或甘油等补剂，如果钠和水分摄入不足，也无法获得最佳的泵感。硝酸盐是提升一氧化氮水平的有效途径，但其吸收速度较慢：芝麻菜大约需要一小时，甜菜根则需要两到三个小时。相比之下，硝酸钠等补充剂能更快地提升硝酸盐水平，同时还能补充钠。
睡眠、阳光照射和抗氧化剂对一氧化氮的产生至关重要。 睡眠不足会损害内皮细胞的功能；阳光照射能促进一氧化氮的产生；抗氧化剂则能减少活性氧的产生，从而保护一氧化氮。在补充剂方面，N-乙酰半胱氨酸（NAC）可以提升一氧化氮水平，但也可能导致多巴胺钝化，因此需要谨慎使用。亚甲蓝则可能抑制可溶性鸟苷酸环化酶，从而降低一氧化氮的功效。
饮食方面，芝麻菜是提升一氧化氮水平最有效且最便捷的食物，其次是甜菜根和其他绿叶蔬菜。 虽然芝麻菜略带苦味，但其高硝酸盐含量使其成为理想的选择。烹调会降低芝麻菜中的硝酸盐含量，但影响有限。芝麻菜与西地那非联合使用，能显著增强勃起效果。此外，碳水化合物对一氧化氮的产生至关重要，低碳水饮食可能会降低一氧化氮水平。
关于勃起功能障碍的治疗，我的研究发现小檗碱可以长期抑制PDE5酶的表达，从而提升一氧化氮水平。 此外，心理因素的影响不容忽视，压力、焦虑等负面情绪都可能导致勃起功能障碍。因此，保持积极乐观的心态，例如进行体育锻炼、户外活动和社交，对改善勃起功能至关重要。
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05:16 我一直对生物黑客很感兴趣，即使在20年前，我就开始尝试优化我的生物机能，包括身体和精神方面。
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05:59 我对生物黑客的兴趣源于对自身生物机能优化的追求，以及对提升自身状态的渴望。
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09:38 影响健身泵感最大的因素是钠和水分摄入。
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11:39 检测一氧化氮水平的最佳方法是使用唾液测试条，尽管它并非完美，但可以作为一种有效的替代方法。
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13:58 我通过严格的纪律和多次重复测试，对超过1000种化合物进行了测试，以评估它们对一氧化氮的影响。
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23:00 除了L-瓜氨酸，睡眠、阳光照射和抗氧化剂等因素也对一氧化氮的产生有重要影响。
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36:49 我最喜欢的提高一氧化氮的食物是芝麻菜，其次是甜菜根和其他绿叶蔬菜。
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40:43 勃起功能障碍的一个主要原因是内皮功能障碍，这会影响一氧化氮的产生。
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51:06 非那雄胺、睡眠不足、吸烟和饮酒等因素都会损害勃起功能。
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56:28 卡图巴可以提高多巴胺水平，并改善情绪和自信心。
00:00
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01:06
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01:28
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01:52
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02:15
are only applicable to those listeners who are based in the US. If you are outside the US, this information does not apply to you. It is not intended to provide medical advice or to take the place of medical advice or treatment from a personal physician. All viewers of this content are advised to consult with their doctors or qualified health professionals regarding specific health questions. 语法解析
02:39
Thank you for listening to the Boost Your Biology podcast. My name is Lucas Owen. I uncover the most cutting edge health information on the planet, ranging from hormones, nutrition, supplementation, fat loss, biohacking, longevity, wellness, and a whole lot more. Welcome to the Boost Your Biology podcast. 语法解析
03:04
What is up, ladies and gentlemen, and welcome back to the Boost Your Biology podcast. Today, I'm super excited as we'll be looking deeper into biohacking erections, improving nitric oxide production, and male sexual performance. Joining me in the podcast studio all the way from Bulgaria, we have Semtex. 语法解析
03:26
Semtex, welcome to the podcast. Glad to be here, Lukas. I've been following you for a long time, so pleasure is all mine. Awesome. I just thought of something. I was going to say that we interacted on Facebook because early on I was part of your Ice in the Desticles group. And we had exchanged some messages, but just now I remembered that on Discord, 语法解析
03:53
in the Pharma PE server. Pharma PE stands for Pharma Penis Enlargement. So maybe a year ago, someone joins in and his nickname is Lucas Owen from Boost Your Biology. And he has your picture as his profile picture. I'm like, yeah, that could be him. Why not? And we exchanged some brief messages, very normal communication. 语法解析
04:17
Months later, he starts spewing some crazy stuff in one of the channels and I'm a moderator. So I'm like, okay, this is definitely not Lucas. I banned him. I deleted his comments and that was it. And then when you messaged me on Reddit, I'm like, 语法解析
04:32
Might be fun here. Is this the same guy? And then I look into your profile and I was like, okay, this is the real Lucas. Wow, that's crazy, man. Yeah, I've had a few people try and sort of replicate my name or my content. But on Reddit, I discovered you. 语法解析
04:50
by looking through different subreddits and I discovered one of your particular, like your highest upvoted thread, which was nitric oxide boosters to aid PE and erections. I tested over 70 results inside. So maybe do you want to share with my listeners a little bit of how you got into the biohacking space? Oh, man. I mean, I think I've… 语法解析
05:16
almost always been into it. I mean, ever since I can remember, I've always tried to kind of like optimize and hack anything, anything, anything that is in my biology could be purely physical, could be mental. And I always found, found it completely normal. And I believe that, 语法解析
05:35
Everything we do as human beings is always to go from one state to a better state, even when we suffer consciously, like working out. It's always with the intent to upgrade ourselves in some way. So I've always been interested in this. Even 20 years ago, I remember I was day trading and I just noticed like there are some days that my brain is working better and some days that it's not. I'm like, how can it work better? 语法解析
05:59
every time. And I think only piracetam was available back then because that was many years ago. And then when it comes to specifically erections, I was very focused on 语法解析
06:14
sport performance, longevity. I never even looked into anything corrections. I mean, we don't have a problem. We just don't think about it. But then I got, not sure how you to piece with censorship, but I got the thing that is like the flu, but not exactly the flu. And, um, 语法解析
06:34
very mild symptoms, but at the end of it, I started getting weird neuropathy symptoms like nerve pain all over my body and that eventually manifests in what is called pudental neuralgia. So somehow the pudental nerve is damaged, let's call it, or yeah, let's call it damage and not fun. In my case, it was like electricity going through your penis 24/7. 语法解析
07:02
So I started looking into ways how to, of course, improve the conditions. No doctors could help me. And I started reading a lot about when you get into that, you get into this space and you find lots of people who have similar conditions. Some, many actually injured themselves via different manipulation of their penises. Like weirdly, aggressive masturbation was the number one thing. And 语法解析
07:32
When you start digging into the research, you eventually get answers to questions you don't have. And you meet people online where you're like, oh, I know this. I mean, I've read the research. I can answer this person. And then I just got intellectually hooked on it. I don't know how it happened. I mean, I started reading everything and anything I could find. And yeah, nitric oxide is the main signaling molecule that is a driver for erections in 语法解析
08:00
and many other things, I mean, still interested in spot performance, 语法解析
08:04
So I started looking into different combinations, but I always wanted to be able to quantify what I'm taking. Is it really having an effect? Maybe it could be placebo. Yeah, the pump is a nice proxy or even your erection, but erections are so… It could be anything. I mean, it could be today you're just too horny or anything. So that's how I got into it and eventually started testing all these different nitric oxide supplements. 语法解析
08:32
And the combinations that I haven't posted about because I'm dreading the word babies. Awesome, man. Yeah, I guess it's like a sheer fascination with understanding biology and then being able to modify it and hack it. And you mentioned something there around the pumps in the gym. Let's start there because it's not necessarily sexual health and sexual performance for men, but… 语法解析
08:58
What have you noticed to be the biggest factors affecting your pumps in the gym? Wow. 语法解析
09:08
Honestly, if I have to pinpoint one thing, it's probably, okay, it's going to be two, but they're jointed. It's probably going to be sodium and hydration because I've noticed that if I'm low on sodium and I'm not way hydrated, no matter how much L-citrulline or glycerol I take, it's not the same. You don't get the same splitting pump. So if I have to just, yeah, if I have to pick one, it's got to be that. 语法解析
09:38
And if we get away from sodium, people will be like, oh, this is boring sodium. Thanks, guy. L-citrulline works. Of course it works. Direct nitride donors, in my opinion, work better, but they're harder to time. So, for example, I know you've been talking at least in the past a lot about 语法解析
10:00
arugula because it's the highest content of nitrates and i've been doing the same thing like you i mean getting like a handful of arugula before a workout but it's hard to it's hard to time sometimes i'm good in one hour and sometimes like what's happening coming and i have the strips i cannot even register in one hour so i have to wait and then oh at hour two now i'm at this level that i wanted to be but i'm not in the gym anymore so 语法解析
10:27
Arugula and beets, beets are even worse. They take probably two to three hours for you to absorb the nitrates. But if you use something like beta nitrate or sodium nitrate, they're used in different supplemental formulas. Do you think the sodium nitrate, just going on that, the sodium nitrate, you're actually getting… 语法解析
10:51
A portion of it as the sodium. So you're getting the sodium benefit and the nitrate as well? Exactly. Yeah, because I think it's around 18% sodium and the rest is nitrates or something like that. I don't remember exactly the percentages of the composition, but it's something like that. So definitely you're getting sodium on top of that and that works well. 语法解析
11:13
Now, going back to because my audience, I doubt anyone has regularly checked their nitric oxide levels. Just explain to people the method or like what's the best, the gold standard way to check nitric oxide levels? Okay, so the best, the gold standard way will be for you to go into a clinic and have them check your nitric oxide levels. But we cannot do that. And even by the way, even in clinical settings is kind of hard to do. It's very short half-life. 语法解析
11:39
But what we can do is we can use these strips. They're sold on Amazon and everywhere that you can check your nitrate saliva level. That's a good proxy. Now, it's true that if you just take, let's say, L-citrulline, 语法解析
11:56
and you check your nitrate levels, you're not going to see a huge bump. Not the same like if you take arugula or beets or anything that has an actual nitrate content. So that is true. It's not going to be the same, but 语法解析
12:11
Nitrate, you can use it as a proxy. So anytime you increase nitric oxide via whatever means, for example, L-citrulline, it will provide substrate for enos to actually create nitric oxide. That will spare nitrates. So this is why you see a bump. Now, is it perfect? For example, can I understand is… 语法解析
12:36
100 grams of arugula better than 6 grams of L-citrulline with this strip? No, because the arugula will beat it always. But what I did, and I didn't post about this, by the way, so you're the first hearing it. So what I did is I used arugula as my base and I used the same brand over 100 times just to check if everything 语法解析
13:00
every time I take 25 grams I'm at this threshold level on the strip so I know 25 grams will always get me here it's a doesn't matter what the level is it's just a it's just a proxy it's a proxy yeah yeah so then if I now take pine bark extract which is not giving me nitrates it's only sparing nitrates because it will upregulate enos and if I go up then it has actually done something 语法解析
13:30
it has actually had an effect because I have spared these nitrates. So this is what I did to test over 1000 compounds. It took me three years and I had to be extremely diligent. I had to literally don't eat nitrates out of these windows because I want to test like, I want to have like a morning test and an evening test so I can have like get two tests a day. Otherwise it will take me like 10 years. 语法解析
13:58
Well, can I just say how much respect I have for you for being able to be that disciplined and to do that, you know, N equals one experiment of yourself. But now you've got that data and you published it online. Are you planning on setting up like a blog or something to share those results? No, I wanted to make a post, but I was afraid of the work that it requires because it's so much. I could just simply be like, 语法解析
14:26
this, this, this, this, this, this is what the data shows, my personal data, but any good test or bad test or whatever, I confirmed it many times. So this is why it took so long. I couldn't just take one thing and be like, all right, this is a home run. I have to retest it many times. And I wanted to explain all the mechanisms. Why am I even testing this? So for example, sometimes I wouldn't even test something that increases nitric oxide. So for example, 语法解析
14:56
Garlic doesn't increase nitric oxide, but it decreases hydrogen sulfide, which actually works as a substitute for nitric oxide. So you're getting the effect. You're still stimulating soluble guanylate cyclase, which increases cyclic GNP. So you're getting the same effect. And this is why when you take, for example, 语法解析
15:21
when I take, let's call it, arugula and garlic extract or even raw garlic, but it's inconvenient, you see this bump on the strip because you're sparing these nitrates. You're using the hydrogen sulfide. Within how long is it usually with the rocket? What's the baseline rocket arugula? For me, it's one hour, but I do it fasted. If I take it with food, then it's unpredictable. Then I cannot even… 语法解析
15:48
All those times where I was accidentally, see, I didn't have this data. So I was making the mistake of going before going to the gym, I would have it just before leaving the house, which means that the effect may not have even. Yeah. How long does it take you to get to the gym? 语法解析
16:07
Like 10, 15 minutes. So really, yeah. I was doing the same thing in the beginning. I was just shoving it in my mouth and then leaving. And probably, yeah, 15, 20 minutes later. Because I thought there was some degree of nitric oxide that was formed in the mucus. 语法解析
16:24
mucosal membrane in the mouth you will probably you will probably get some but at least these strips that i was using and i tried many different brands just to be sure that i'm getting the similar results and um are the strips just to confirm the strips are urination oh sorry saliva yeah it's alive so you you basically uh 语法解析
16:49
I'm not sure on some strips they say but I didn't use those. They say that you shouldn't like directly place it into your mouth. I don't know why so you have to spit in something and dip it and just leave it but it doesn't matter so how you do it within 10 minutes the color settles and you can check it on the bottle you can see okay now I'm here and 语法解析
17:16
the one brand i'm not going to recommend the brand because they actually screwed up their strips i don't know why and probably i had like 20 more things to to test but they yeah they totally messed it up now the all the the strips are too pale and they don't correspond to the they change the the coloring schedule now it's all all messed up but they actually had like numbers so the target was um 语法解析
17:42
440 something yeah 440 and you can see that this is target and this is this is high and yeah i wasn't striving for target because i'm not sure what they mean by target it was based i think on uh actual good science because every time i was in target i could get a proper pump in the gym for real and when i was at this level that is high it was even a better pump so yeah 语法解析
18:08
You know what you said before, you mentioned something about like sodium being a really important factor. I might mention that I've always when I do my blood tests, my sodium levels, according to the blood test, are always on the lower end of the reference range. And I've always been frustrated by it. Because most people are worried because it's too high, right? Most people are. And my blood pressure is also very low. So… 语法解析
18:34
Over the years, I've found that anything that lowers my blood pressure any further and lowers sodium or accelerates sodium excretion, I definitely feel weaker and worse pumps in the gym, a lot worse. Yeah, I have experienced the same, I would say. So the last time I checked sodium was long ago. It was low for me too. My blood pressure is low. And yeah, yeah. 语法解析
19:04
uh for real so for example if if i take something that really lowers blood pressure like a medication uh i have to mean like a low low dose sialis or for example yeah for example i have to i have to manage it i'm not gonna get away with just taking it i have to be hydrated i have to take sodium and you're right if i just take it i'm not gonna get although i'm 语法解析
19:28
To be fair, Cialis doesn't give me good bumps in the gym. For me personally. Yeah, it's not… Wow. Yeah, it's not like… 语法解析
19:37
It's not like, for example, if I take L-citrulline or nitrate. Now, with the citrulline, specifically just the citrulline or the citrulline malate versions? I've used both. I think for sport performance, the malic acid is beneficial. But if you're not using it for sport performance, let's say you're using it just for the purpose of better erections, it would actually make sense to use L-citrulline without the malate because… 语法解析
20:05
It diverts resources from where you want the L-citrulline to actually go. And the malic acid is more for better muscle function, getting it more into the muscle itself. 语法解析
20:18
Did you find that there was a dose-dependent effect? The higher the dosage, the greater the outcome? Yeah, of course. So at what point was there actually an impact on your nitric? Was it like two grams of citrulline? So that's interesting. Even three grams of L-citrulline, 语法解析
20:40
actually registered a sparing effect on the nitrates on the strip. So even three grams registered something, it's already having an effect. And there is literature, by the way, that you can see that they tested specifically. They took L-citrulline and they could see that L-citrulline is then converted into nitrates. So it has this, it is this machinery where, okay, I have enough nitrates, 语法解析
21:08
I'm going to use them for nitric oxide or okay I have enough nitric oxide from let's say endothelial nitric oxide synthesis I'm gonna actually convert some into nitrates I'm gonna spare it I'm gonna use this later so it's a it's a beautiful machinery um and but three grams 语法解析
21:26
you're not going to have like a meaningful impact on bumps in the gym. Six, I believe is definitely there. And some people take 10 grams. I've heard people taking 15. It's an overkill for me. Even, yeah, 10 grams for me, I would say is better than six. Yeah, there is this. And I'm not sure what exactly the U shape. Is it similar timing in terms of arugula or? 语法解析
21:57
Or is it a faster one? It's super fast. You want to take it like 30 to maximum 60 minutes before you want the effect to kick in. Wow. Interesting. 30 minutes for me is enough. Did you end up ever… Sorry. Apologies. But if you actually want to test in a strip, it's going to take a while because you want this to convert to nitrate. So, oh, now it registers. But… 语法解析
22:24
Purely in terms of effects, 30 minutes, let's call it 45 is perfect. Interesting. All right, let's go back to, because I'm getting too excited about different topics. Let's go back to… 语法解析
22:39
Guys listening to this are probably wondering what are some other factors that you think will contribute to better nitric oxide production in the body? Because obviously citrulline is one factor, but obviously there's many other factors. What else do you think plays a crucial role? All right. So for you to even use citrulline, 语法解析
23:00
which gets converted to L-arginine is better because it survives this first-pass metabolism. It gets converted in the kidneys into L-arginine. And now the endothelial cells via endothelial nitric oxide, they're using L-arginine to actually produce nitric oxide. So if someone has any sort of dysfunction when it comes to ENOS, endothelial nitric oxide, they're not going to take… 语法解析
23:29
they're not going to receive the same benefits. And when I talk to some, let's call them older gentlemen on Reddit, they often report like, well, I need 10 grams of citrulline. What are you even getting from five? Or they get nothing. And usually those are people with some level of endothelial dysfunction. 语法解析
23:49
So if you want to really take care of it, you can take stuff that upregulates ENOS and the activity and the end. You can actually upregulate the transcription, the expression of ENOS, and you can take something that directly affects the activity. So stuff like 语法解析
24:10
pine bark extract or, uh, grapeseed, um, or garlic acid. I think the highest content of garlic acid could be found in, uh, 语法解析
24:22
pomegranate extracts, stuff like that. They will upregulate enos. And of course, the best thing will be BH4. You've talked about it. But you know, it's super expensive. It's cost prohibitive for anyone. Let's talk about that. No one is talking about BH4 on YouTube. I don't see anyone talking about it online. But this is a crucial… Well, there's some people, but not in the mainstream. Not on the 语法解析
24:51
Honestly, it's the only you talk about. Oh, really? Okay. No, I haven't heard of anyone else. Well, I learned about BH4. It's called tetrahydrobiopterin. That's the name, tetrahydrobiopterin, as a cofactor for the catecholamines. It's like part of that cascade as well. What I might do, I want to create another dedicated YouTube video to this topic because 语法解析
25:19
There are ways to upregulate BH4 production. I think it was vitamin C plays a role. Folic acid. Which one? Folic acid. Folic acid, yep, that makes sense. 语法解析
25:32
Does SAMe? I don't know if SAMe does that. Yes, yeah, it should. I think there's literature on it. Yeah, there is. And yeah, just the B vitamin group is super important, of course. I think the most crucial piece is folate. And direct supplementation would be awesome, but it's just so expensive and hard to get. I'm not sure it's sold in one or two places. 语法解析
26:01
I've never acquired it. I've never personally had it. I would like to try it. I'd be happy to try it. I'm sure you would as well. Yeah, I think they didn't ship to Bulgaria, the place that I found a few years ago. I was going to buy it just for the test, even though it's super expensive, but they didn't ship at all. Do you think that maybe the reason why no one has synthesized it into a supplement form is probably because it… 语法解析
26:31
it degrades or something or it's not stable or what do you think honestly i haven't uh i haven't looked super deep into that but i don't think um yeah it's it's not super stable but they found a way to put it into a supplement i'm not sure if they call it medication but at least supplement there were two brands that were selling it uh and from what i saw 语法解析
26:56
They didn't use any special formulation. Maybe they didn't disclose it because in a supplement you can do anything. But yeah, I think that's the main reason. And you don't need a lot of it, but I think it's just cost prohibitive. I don't know why it's super expensive to produce it. I think that's one of the things, one of the main factors. 语法解析
27:21
Yeah, well, let's go back to that topic of like enos, you made some, you actually mentioned some great examples. So pine bark, grapeseed extract, pomegranate extract, like these all upregulate enos. Then obviously, you got the important cofactors, so like vitamin C, you know, the B vitamins somehow indirectly haven't having an effect. 语法解析
27:43
What are some other factors that influence nitric oxide that you've also researched? Maybe like light exposure, sleep, things like that. So sleep for sure is super important. There is research on it that you're just not in the best state possible. Your endothelial cells are not functioning optimally if you're sleep deprived. That's not a surprise. Nothing is functioning optimally when you're sleep deprived. 语法解析
28:12
There is, I think, solid research on sunlight. And just recently someone asked me, hey, did you in your experiments, did you actually try sunlight? And I was like, no. Why? Why didn't I try this? Because it would be easy to see if I just spent 语法解析
28:29
one hour in the sun after eating arugula, if that alone will have this sparing effect on nitrates, which means that it will actually boost nitric oxide. But the literature is there that definitely affects it. And one of probably the most important factor is a reactive oxygen species that I believe it's number one. And this is why antioxidants work. And 语法解析
28:54
People I think in the health space are a bit afraid of overdoing antioxidants and you know don't take vitamin C after a workout it would blunt the effect. I agree that there is this blunting effect but to be honest let's say you take vitamin C after every workout. I should do this experiment I should take two grams of vitamin C after every workout. 语法解析
29:18
and you don't get jacked at all, it's not the vitamin C. It has some effect, but it's probably your effort. It's probably your nutrition. So while I wouldn't take vitamin C right after the workout, I honestly don't worry about taking antioxidants, but I also don't overdo it. But there are crucial piece, and we actually have evidence for it because there are so many, well, not so many, but five, six, I mean, that's enough studies that show that if you take vitamin 语法解析
29:48
Okay, there are three, I remember, three exactly. If you take glutathione with L-citrulline, you're getting… 语法解析
29:56
much higher levels of L-Arginine in plasma and in OX. So yeah, more nitrates, more nitric oxide, more L-Arginine in plasma if you take Glutathione with L-Citrulline. And they even used an inferior form of Glutathione. They used just reduced Glutathione, which, you know, it's not very absorbable. They could have used Liposomal, which would be the best. They could have used Acetyl-L-Glutathione, which is really good. 语法解析
30:24
And yeah, of course they could have used NAC, N-acetylcysteine, which would upregulate glutathione synthesis, but I'm sure it will work. N-acetylcysteine definitely shows on my tests and just subjectively that it bumps NO, nitric oxide, but I think some people don't like taking N-acetylcysteine 语法解析
30:52
I'm one of them. Do you have this blanking effect? I do, man. I do. I do. Yeah. I can't, I can't, I can't use, unfortunately I cannot use NAC for that main reason. You know how they study it for, so N-acetylcysteine studied for like addictions, obsessive compulsive disorder, things like that. But NAC, 语法解析
31:15
If you don't have that, which I don't have that, and then you take it, it's going to blunt. For me, it was starting to blunt the effects of natural things that should be pleasurable, which is not a favorable effect. It's an anhedonic effect. And a lot of people on Reddit have also reported the same negative effects of NAC. Yeah. 语法解析
31:34
It's very real. I would say that I'm not susceptible to placebo-nocebo at all. And I didn't even know about this when I started taking antistilled cysteine years ago. And at some point, they… 语法解析
31:49
I'm like, something is off. I mean, I feel different. You're having the blunting effect within a week or so. Yeah. For me, it's fairly quickly. But I can use it acutely with great success. I could use it like two days in a row, three days in a row, or just occasionally, and I'm fine with it. I'm really conflicted because it's actually, it has so many benefits. You've read the literature. But at the same time, there are these things 语法解析
32:18
two little things that it blunts dopamine for some people and it's actually a pretty potent biofilm disruptor. It's very mucolytic so you probably shouldn't take it like chronically because yeah this is also something that is very well elucidated in the literature and it's although some people take it for years and then don't have problems. 语法解析
32:44
What about did you come across any specific like supplements that accelerate nitric oxide degradation, like basically lowering nitric oxide? No, because I never looked for them. But do you have anything in mind? Do you know what? I accidentally did find one. 语法解析
33:07
I'm pretty sure phenylalanine can slowly inhibit nitric oxide production. And also another supplement that's well-known is methylene blue. Okay, so methylene blue for sure. It makes sense. Methylene blue is an inhibitor of soluble guanylate cyclase. So this is how nitric oxide is not actually – 语法解析
33:35
doing its effect because it cannot if it cannot bind to soluble granulate cyclase it will never increase cyclic GMP you will never get the actual vasodilation so that's true I think I think methylene blue requires 语法解析
33:53
according to the literature, of course, requires really high dosages to actually inhibit and block SGC. But again, anecdotally, people report worse pumps or some people report worsening of erections when they take methylene blue. I'm not sure if they take a lot or if they take it for too long. I haven't experimented with methylene blue a whole lot. I've taken it, of course, but… 语法解析
34:21
Yeah, I'm not very well. I know it's the hot topic right now. I'm not very well familiar personally with methylene blue. Do you have a lot of experience with it? Yeah, yeah, yeah. When I first tried it, I would have been probably like six years ago, a long, long, long time ago. I came across it on a really cool podcast called Smart Drug Smarts. It was one of my favorite podcasts. I remember this. What happened to that? No way. Weird. 语法解析
34:46
You remember it. Yeah. Did it disappear? No way. I can't believe you know it because everyone that I talk about it to, everyone's like, I've never heard of it. Yeah. It was super informative and they were on top of the science. They were basically zero speculation, but I think they're gone. I've never- They're finished. They finished a long time ago. Yeah. Yeah. They finished a long time ago. It was one of my favorite podcasts. I learned so much. And there was an episode where- 语法解析
35:12
where the host interviewed an expert on methylene bloom was talking about low doses versus high doses. And I remember hearing them say about it's sort of scavenging nitric oxide. And I ended up trialing it. I never went above five milligrams, which is still considered moderately low dose. But I found that 语法解析
35:35
Like, even looking down below, I'm like, okay, there's definitely some sort of atrophy, you know, some shrinkage going on there. So I'm like, I'm not a fan. Yeah, I can definitely see that. Because if it has the effect that the scientific literature says it has, you're simply going to be in a more contracted state at all times while it's active. Yeah. 语法解析
36:06
In terms of what else have you… Obviously, you're mentioning before the free radical damage. Oxidative stress being a crucial factor affecting nitric oxide production. Let's talk about nutrition because obviously, because there's guys listening to this that want to know what foods should they aim for. I've got some of my own favorites like, for example, pomegranate juice, arugula, 语法解析
36:35
citric, maybe sometimes some oranges. Do you have any personal favorites in terms of foods for nitric oxide? It's by far arugula. It's so easy for me. First of all, I love arugula. I love it in a salad. 语法解析
36:49
On its own, I'm not going to say it's the best thing in the world. It's too bitter to eat. But I eat for performance. So I just literally just grab it, shove it in my mouth, and that's it. So when it comes to just getting the effect, this is what I do. Beats for me are inconvenient because there's literally… 语法解析
37:11
We don't have beetroot juice here. They just don't sell it. So then I will probably be, okay, this is very convenient. I can just chug it. So I have to buy beets. I have to like cut them up, eat them. So I'm not that lazy, to be honest, but I'm doing so many things. I just want something to be fast. So arugula is number one. 语法解析
37:33
But I do eat beets, to be honest. And other leafy greens have some impact. I've tried to get some good response eating kale and spinach. And what can I say? I mean, they don't have the same nitrate content as arugula. So it was not a surprise. But I do love them. 语法解析
37:54
And you know what? People, when we talk about green leafy vegetables, people are worried about oxalates and stuff like that. That's a whole another topic that probably should have more focus on it. But arugula actually don't even do that. So this is something that you shouldn't even worry about arugula. As in what you're saying is arugula is basically zero oxalates, right? Yeah. 语法解析
38:22
Yeah, that's… It doesn't have this effect like spinach will have. So I'm not going to speculate, but from what I remember, it's either zero or close to zero, while spinach… 语法解析
38:36
People are genuinely worried about it. I wouldn't be, but that's another topic. And so if you can just eat arugula and you love beets, I think that basically covers it. What about, this will be a tricky one, do you think does heating or cooking the arugula degrade the nitrate content? 语法解析
38:56
Yeah, to some extent, but not a lot. Yeah, to some extent. I've never actually tested it because that would just take time. And I wanted to be as lean as possible in this experiment so I can actually finish them. But yeah, it makes sense. I mean, it should degrade it to some degree, yes. 语法解析
39:18
There was also another really interesting study. I don't know if you saw me post it, but it was about how arugula can change the pharmacokinetics of sildenafil or Viagra in rats. And they found that arugula combined with Viagra made them like it actually helped their 语法解析
39:38
more so than just Viagra alone. Yeah, of course. A combination of both. You have this direct donor of nitric oxide and sildenafil is directly dependent on nitric oxide. So for example, I just posted… 语法解析
39:53
This took so much work. I just posted this article about how to deal with PDE5 inhibitors, non-responsiveness. There are so many people, I'm surprised, many young people who don't respond at all to, at all or just weekly to the Dalafil, Sildenafil. The brand names are, of course, Viagra and Cialis. And there are many reasons why people don't respond. And this is, 语法解析
40:23
Probably one of the number one reasons when you look at the different conditions, health conditions, comorbidities, when people don't respond to PDA5 inhibitors, one of the main reasons is actually some sort of endothelial dysfunction. Could be metabolic syndrome, could be atherosclerosis. So you're basically not producing the nitric oxide. 语法解析
40:43
you don't have high enough levels of cyclic GMP, PDF5 inhibitors would inhibit the breakdown, but there's nothing to inhibit the breakdown of. So this is why arugula plus sildenafil works. I've taken this so many times. Of course, yeah, it works so much better. 语法解析
41:05
And also historically, I believe arugula is considered to be an aphrodisiac, like the vegetable itself is considered to be like a, you know, a good for sexual performance. You know what I found that I was actually surprised because reading so much about arugula that was news to me, it actually, it turns out it contains ichorin, the same… No way, as horny goatweed. Yeah, as horny goatweed, yeah. 语法解析
41:34
Yeah, I just read this like a few months ago. It's apparently, so I was, they were using a different name, one of the many names of arugula. And I was just reading, reading, I was like, let me check with this plant. And it's arugula. So it contains ichorin. I'm not sure how much ichorin contains. And honestly, I'm not a… 语法解析
41:55
believer in icarin because it's so much weaker so so it's 82 times weaker than sildenafil let's call it 80 because we don't know exactly every time we test sildenafil there are differences in the ic50 values and i've taken i think the most i've taken of pure icarin is three grams and uh yeah it barely does anything on its own so i wanted to take 语法解析
42:22
I was thinking, okay, so 1.6 grams should be equal to 20 milligrams of sildenafil. But it doesn't even touch 20 milligrams of sildenafil. But horny goldweed works, actually. It has some sort of an effect, more of a libido effect, I think. And so there are many different constituents in horny goldweed that potentiates 语法解析
42:52
Maybe erections, definitely something to do with libido. And arugula might be in the same boat. Very interesting, man. Because I want to, yeah, I've always wanted to understand like the key constituents of different herbs and extracts. And I guess in terms of like, I mean, do you think fats, carbohydrates and proteins, like have you, I'm sure you played around different diets over the years, right? 语法解析
43:21
Do you feel like they have any dramatic effect on nitric oxide or it's a bit hard to say? I'm going to say that in my personal experience, if I'm extremely low on carbs, I don't get the same effect at least. Now, when you're in the gym, of course, you're deprived of glycogen. You're not going to have the same pump. But I feel like even if you use other measures to assess how well nitric oxide works, 语法解析
43:51
It's working for you. I feel like when I'm low on, extremely low on carbs, it's not the same. So that's one thing that I can say, although I'm sure many people can make keto work for them. I'm not against it or anything. I've tried it. I mean, I've been months on keto. Of course, you're going to try everything when you're trying to improve yourself. And it has some benefits, as you know. But I definitely prefer to have… 语法解析
44:18
Let's call it enough carbs in me for everything to work properly. I'm the exact same. If I… 语法解析
44:25
If I go low carb, everything else just starts to eventually just fall to shit. Basically. I just, I don't feel good. I don't feel good. And it's, it's, it's kind of weird because it's not immediate. Yeah. You, you get the keto flu, you, you know, you fight through it and then you're like, Oh, now I feel so clean. It, everything's perfect. My mind is working on this super level and, 语法解析
44:50
And then it's the grades. You go back to baseline. You go below baseline for me. And two months later, you're like, yeah, I don't feel well. I mean, I need carbs. What do you think about it? Oh, for sure. I mean, low carb is a recipe for high cortisol. And also like low carb equals high cortisol, high sympathetic tone, you know, sympathetic activity. And then also low, 语法解析
45:20
lowers free testosterone, and then also lowers thyroid hormone. So it's not good for anything. And then you need thyroid hormone to create DHT. I think carbs are crucial. I know that it's almost crazy that now this is probably a hot take when you tell someone that carbs are actually important. And I believe the low-carb movement is very beneficial for people 语法解析
45:47
Different populations that need to lose weight, need to control their appetite, that's all fine. We now have drugs that do a better job at controlling appetite. They have their own problems, of course. Almost nothing is a free lunch. But carbohydrates are very, very important. And when I look at, when people send me their blood work and ask me questions, and I see like sky-high SHBG, I'm like, are you low-carb? 语法解析
46:16
It's 99%, yes. And then it always drops when they introduce carbs. So that's clear as day. Yep. No, I'm glad you mentioned that. What about berberine? Because I want to talk about down-regulating PDE5. Berberine is a long-term way to reduce that, right? Right. So berberine will have almost no effect on the – 语法解析
46:46
on the protein level of PDE5. So it's not like you're going to take it and you're going to experience erections similar to Cialis or Tadalafil. You know this. I'm saying this for everyone to know. But what it actually does is it downregulates the expression of this enzyme, which means that over time you should on paper start producing less and less of it. So now you have 语法解析
47:08
Less PDA5, it doesn't break down cyclic GMP. This is what you want. Cyclic GMP is what leads to vasodilation and you get better erections, better pump and everything. 语法解析
47:20
So they tried this. Of course, it's a rat study, but they specifically tested the mRNA expression of berberine in the penises of the rat. So it's very specific. It's good data. Some people hate rat studies. I love them. I mean, they're the first step. We need them. And on paper, if you take berberine for a long time, you should experience… 语法解析
47:50
lower production of this enzyme that is degrading cyclic GMP. Now, how can we test it? We cannot. Personally, I have seen that if I take it for a long time, it has this effect. Everything is better. And you can also quantify this, not just subjectively, you can use a tracker to track your nocturnal erections and see exactly what's happening. And also, hmm, 语法解析
48:21
I'm not sure how the dosages, if you translate the dosages, you don't need a lot. You need like maybe 500, 1000 milligrams. Some people have problems with that. I don't. It rarely disrupts me in any way. So berberine is one way that this could work. Icarine does the same thing on the mRNA levels, but it doesn't do that good of a job at that. 语法解析
48:46
But I was wondering of running the experiment when I'm actually taking something like not anything dangerous like sodium valproate, but maybe like sodium butyrate or tributin, the better version, along with berberine for a few months and then assessing if this is actually really inhibiting the production of PDE5. Yeah. Did you just mention sodium valproate? 语法解析
49:12
What's the, in, in, cause, um, in what context? Cause that's a, like, is it for fear elimination? Is that? The age for age deck. Oh yeah. So you could on paper, this is very speculative. You could on paper, uh, use it to, since you're, 语法解析
49:34
since you're manipulating with berberine the gene expression of this enzyme, you can help with HDAC inhibition. Sodium butyrate is probably, it's way safer. So for sure, I don't recommend anyone touching sodium valproate. And also tributin, which is 语法解析
49:54
I think, consider the supplement, at least here, you can just buy it freely, is the better version of sodium butyrate. And that could also help. But berberine is very interesting, man. They use it in intracranial injections, penile injections for rats, and it actually induces erections. So that's interesting. 语法解析
50:21
They're not even sure why exactly. I mean, they have hypothesis, but they're not sure why exactly that's happening because it doesn't have the direct effect on PDE5. And also there are human studies where they form the topical gel with berberine and they use it on the glands of the penis. And that helped with erectile dysfunction. And weirdly, it helped with premature ejaculation. 语法解析
50:45
Let's shift gears and talk about erection killers. Okay. Specifically, maybe let's start with like probably the worst things that guys could be doing. Like maybe it's finasteride, in your opinion, like go down the list. Okay. So finasteride is, of course, always a hot topic. I'm… 语法解析
51:06
Probably right in the middle when it comes to Finasteride. There's something in there happening, we cannot deny this. Of course, there are too many people having these side effects. 语法解析
51:16
Could it be that people are also suffering a bit from mass hypnosis and people are getting, especially young guys, I mean, they're worried about their experience, they're losing their hair, now they're taking finasteride, they're super worried that it's going to affect their erections. Could that be a real noose-y effect? Of course, nobody's disputing this, but also nobody's disputing that it's doing something for real when it comes to, and how could it not when it's 语法解析
51:41
crashing when it's literally lowering your DHT. I think DHT is important for sexual health. I don't need much convincing on that front, but at the same time, could people function absolutely well without DHT just because, I don't know, maybe their androgen sensitivity 语法解析
52:06
is high, maybe their androgen pool is just too large or large enough so they don't need that much THD for the binding of the androgen receptors. Yes, of course. So if it's someone who actually wants to take care of erections, I cannot in good conscience tell them take finasteride because we have 语法解析
52:25
too much uh anecdata when it comes to that so that's one thing sleep deprivation for sure uh is another thing that people should be uh wary of bad that i mean i'm sorry i have to tell this but uh yeah if you're not in shape if you're in a bad shape let's call it you're not gonna be uh you're not gonna have optimal erections that's that's just facts um 语法解析
52:55
Smoking, alcohol, the boring stuff, yeah. But these are actually stuff that are killing your erections for real. And we should probably touch on the fact that many, many people now, very young people, suffer from erectile dysfunction. And I don't have the answer for that. I don't know why that is happening. There are hypotheses, of course, that it's porn-induced, which very well could be. It could be dopamine-inducing. 语法解析
53:24
desensitization because we know that it has this effect, there is enough data. Actually, this will be a good thing to test when it comes to nocturnal erections because they're not psychogenic in nature. So people who abstain from these explicit sexual materials, do they experience 语法解析
53:49
increase of internal erections. Many people report on Reddit, for example, that when they cut corn, they, yeah, now they're getting morning wood back and everything else. So that's definitely one thing. And 语法解析
54:05
And also, I think many people now live very close lives, if that makes sense. I mean, I think they're spending way too much time in the virtual world and they don't connect with people properly. And I'm speaking specifically for guys way younger than me. When I'm talking to them, I'm not getting the feeling that they have the same 20s that I had, like… 语法解析
54:35
connecting with people in real life and these few encounters that they have with women are very new to them and then 语法解析
54:46
Well, guess what happens when you're nervous? I mean, that could happen. That's very real. You could have problem with your erection. And then this just starts this spiral where it's always in their head. So when it comes to young people, I think the psychogenic component is huge. And people should learn to relax, maybe pick up sports, go outside, talk to real people, do something positive. 语法解析
55:14
very physical. I feel that this is crucial. I don't think that unless we're talking about some people that are extremely food deprived and they're competing in bodybuilding, I don't think anyone will have a negative effect on their erections if they work out, do cardio, lift weights. It's always a positive. It's never a negative, especially cardio. People don't like to do cardio, but especially cardio has a huge effect. And increasing your VO2 max will have a 语法解析
55:44
enormous effect on erections. Awesome. Awesome. Now, you mentioned some great, great points there. A lot of different factors going into that. I think the psychogenic aspect that you mentioned there is a really, really big one. That's why, like when it comes to testosterone optimization, obviously, there's, like you said, lifting weights, eating well, getting outside sunlight exposure, no nutrient deficiencies, micronutrient deficiencies, things like that. 语法解析
56:11
That's actually why the very first supplement that I released, I don't know if you saw it, but I released a catwaba. Did you know about that before I released it? Yeah, yeah. I've used it for years. Catwaba is one of my favorite herbs for increasing dopamine. 语法解析
56:28
And I knew you talked about it years ago. And yeah, I haven't tried your brand. I think just recently you mentioned something, you posted that it's now available in the UK. So that means that I can now purchase it. So I'm really stoked to try it. I've used many different brands. 语法解析
56:49
Honestly, dude, over 10 different brands and just even different powders that I found online like Amazon or eBay. I've used so much different brands of Catuaba and some were not even brands, just like loose powder. And it's amazing. I love Catuaba. Well, make sure to just send me an email after this. I'll make sure to send out a bottle. Just send one out to you and say… 语法解析
57:17
You can definitely try that out and to say thanks for coming on the podcast. Yeah, go ahead. 语法解析
57:24
I was going to say, what's your personal experience with Catuaba? What is the number one thing? Of course, it raises dopamine, but how does it make you feel? The number one aspect for me with Catuaba is if I'm ever feeling any doubt or hesitation or lack of confidence or like any sort of low dopamine symptom, Catuaba will always kick me back into gear. It'll get me back into a state where I'm actually like, 语法解析
57:52
the typical dopamine state that I like to be in, the high dopamine state. So I'm more confident, a lot more social, 语法解析
58:00
I'm more motivated, more driven. That's what I love. That's what I love about Caswaba. That's funny you should say that because I think this is practically how I use it. I usually don't start the day with it, but I'm like, oh, it's noon. I'm a bit down or I'm not super motivated. I take it and that takes care for the rest of the day without disrupting my sleep or anything. So it's funny that we're using in practically the same way. 语法解析
58:26
Yeah, no, that's really cool. I'll make sure we get a bottle sent out to you. But look, we spent a good like nine months trying to find real Catawaba because we sent them off to get them third-party tested through Alchemist. They're like a big company in America that tests products. And lots of our samples failed the assessment, which meant a lot of them on the market are actually probably fake. Yeah. 语法解析
58:54
Yeah, probably most of the stuff I've taken is not Cotuaba actually. Yeah. Yeah. So just got to be careful with that aspect. But man, I think we've covered a lot. We've definitely, if my audience wants to like connect with you on Reddit, where can they find you? 语法解析
59:13
So I'm on Reddit, so it's going to be you slash Semtech7, so username Semtech7. And from there on, they can read some of my posts or in the description, there is a invite to my Discord where I post the research I read daily. And they can connect with other like-minded people who dig into the research and try to find different ways to basically optimize their biology. 语法解析
59:40
Yeah, no, great, great stuff. Keep doing what you're doing, man. I'm a follower on Reddit. So I love watching out for good quality content and posts and things like that. So if anyone's listening to this, I'll leave it linked in the podcast show notes, Semtech7, his Reddit channel and Discord link. But otherwise, guys, if you did enjoy today's podcast, please do like this video and please do leave a five-star review. It does help with the ratings and the algorithm stuff. 语法解析
01:00:10
But otherwise, that's it for me today, guys. Thank you so much for tuning in. Semtex, thanks so much for jumping on, man. It was a pleasure having you. It was an honor, honestly. I've been following you for so long. You're an OG in this space. Years ago, nobody was talking about the things you talk, different biohacks. And still this day, I feel like, yeah, you're talking about things that nobody else talks about. So keep doing what you're doing. 语法解析
01:00:36
Appreciate it, man. That's the objective. That's my goal is to share cutting edge health information to the world to reach guys like yourself looking to optimize. So that's it for me today, guys. I look forward to seeing you in the next episode. I don't know about you, but the number one thing I look forward to when I return from traveling is a good night's sleep in my own bed. 语法解析
01:01:00
that has never been more true than it is now that i have a sleep number smart bed i get so sore after traveling on planes but after literally one night in my sleep number smart bed my body feels restored rested and relaxed the fact that my bed actually listens to my body and adjusts to my needs to keep me sleeping soundly all the way through the night is worth it alone not 语法解析
01:01:21
to mention my husband and I never need to argue over firmness because we can each dial in our own sleep number setting. Why choose a Sleep Number smart bed? So you can choose your ideal comfort on either side. And now, for a limited time, Sleep Number smart beds start at $849. 语法解析
01:01:37
Price is higher in Alaska and Hawaii. Exclusively at a Sleep Number store near you. See store or sleepnumber.com for details. What if I told you that right now, millions of people are living with a debilitating condition that's so misunderstood, many of them don't even know that they have it. That condition is obsessive compulsive disorder. 语法解析
01:01:54
or OCD. I'm Dr. Patrick McGrath, the Chief Clinical Officer of NoCD. And in the 25 years I've been treating OCD, I've met so many people who are suffering from the condition in silence, unaware of just what it was. OCD can create overwhelming anxiety and fear around what you value most, make you question your identity, beliefs, and morals, and drive you to perform mentally and physically draining compulsions or rituals. Over my career, I've seen just how devastating OCD can be when it's left untreated. 语法解析
01:02:22
But help is available. That's where NoCD comes in. NoCD is the world's largest virtual therapy provider for obsessive compulsive disorder. Our licensed therapists are trained in exposure and response prevention therapy, a specialized treatment proven to be incredibly effective for OCD. So visit NoCD.com to schedule a free 15-minute call with our team. That's NoCD.com. And now, a next-level moment from AT&T Business. 语法解析
01:02:47
Say you've sent out a gigantic shipment of pillows, and they need to be there in time for International Sleep Day. You've got AT&T 5G, so you're fully confident, but the vendor isn't responding, and International Sleep Day is tomorrow. Luckily, AT&T 5G lets you deal with any issues with ease, so the pillows will get delivered and everyone can sleep soundly, especially you. AT&T 5G requires a compatible plan and device. Coverage not available everywhere. Learn more at att.com slash 5G network. 语法解析
Edit:2025.04.11
分享使用Catuaba的经验，都认为它能提升多巴胺水平，让人更自信、更有动力和社交欲望。花费九个月时间寻找真正的Catuaba产品，很多市售产品可能是假的。
Edit:2025.04.12
Semtex 的生物骇客 (Biohacking) 之旅
一氧化氮 (NO) 与泵感
测量一氧化氮 (NO)
影响 NO 产生的关键因素
促进一氧化氮的营养
PDE5 抑制（下调分解 cGMP 的酶）
勃起杀手
卡图巴 (Catuaba) 补充剂讨论
Edit:2025.04.12
