Over the last few weeks, I ran a quick experiment with different sources of DHA.
在过去的几周里，我用不同的DHA来源做了一个快速实验。
This post will just skim over the details, and represents a brain-dump of current questions that I have. This is by no means an easy-to-read post.
这篇文章将略过一些细节，并代表了我当前的一些问题。这绝不是一篇容易阅读的文章。
Personal Observations
个人观察
First, some important personal background:
首先，一些重要的个人背景:
•I have been eating a lot of DHA in the form of seafood for the last 2 years⇒DHA stores are relatively full
在过去的2年里，我以海鲜的形式吃了很多DHA，所以DHA储存比较满
•My liver has consistently tested incoherent since birth. This puts a limit to the enzymatic pathways needed to process DHA from whole foods. This is mostly fixed with methylation support (mostly manganese and molybdenum). This means that eating seafood is a “stressor” to the liver if not supplemented with the appropriate nutrients.
我的肝脏从出生起就一直有缺陷。这就限制了从天然食物中加工DHA所需的酶途径。这主要是固定的甲基化支持(主要是锰和钼)。这意味着，如果不补充适当的营养，吃海鲜对肝脏来说是一个“压力源”。
Assumptions:
假设：
Algae-derived DHA contains more non-sn-2 position DHA versus sn-2 position DHA (40% sn-2 vs the rest in sn-1 and sn-3 for algae sources, vs about 70% sn-2 in fish)
与sn-2位置的DHA相比，藻类来源的DHA含有更多非sn-2位置的DHA(藻类来源的sn-2含量为40%，sn-1和sn-3含量为40%，鱼类中sn-2含量约为70%)
Though maybe one day we'll breed sn-2 specific algae strains –
也许有一天我们会培育出特定的sn-2藻类菌株
① http://link.springer.com/article/10.1007/s11745-997-0127-8web.archive.org/web/20160520192143/
② http://link.springer.com/article/10.1007/s11745-997-0127-8
On to the results:
关于结果
(“Coherence Testing” refers to biotensor testing of specific objects)
(“相干性测试”是指特定物体的生物张量测试)
•Algae-derived DHA consistently tests for improvements to cardiac and parathyroid function.Coherence is achieved in gate 21 and 51 on Human Design bodygraphs, correlating to acupuncture points of the heart inflow (just above and right of the left nipple region), heart (CV-14), thymus (slightly below collar bone at center line of body), and parathyroid (neck region right below chin)Fish-derived and Whole Food DHA do not improve coherence in these areas.
从海藻中提取的DHA一直被用于改善心脏和甲状旁腺功能。在Human Design人体图上第21和第51实现了一致性，与心脏流入点(刚好在左乳头区域的上方和右侧)、心脏(CV-14)、胸腺(在身体中线锁骨略下方)和甲状旁腺(脖子区域在下巴下方)的穴位相关。鱼源DHA和天然食品DHA并不能改善这些领域的一致性。
•Fish-derived and Whole Food DHA improve coherence in eyes and brain. (Gate 17 and 11 in Human Design Bodygraphs, corresponding to the relevant eye and brain points)
Algae-derived DHA do not improve these areas.
来自鱼类和天然食物的DHA可以改善眼睛和大脑的一致性。(Human Design Bodygraphs第17/11，分别对应眼/脑）
而来自藻类的DHA并不能改善这些领域
•Whole food DHA (seafood) almost always put added stress on my liver. (Gate 25 on HD Bodygraphs, corresponding to LIV-14 point).
Taking molybdenum (approx 150mcg) and manganese (approx 15mg) fixes these issues.
天然食物DHA(海鲜)几乎总是给我的肝脏增加压力。(HD Bodygraphs第25，对应LIV-14)。服用钼(约150mcg)和锰(约15mg)可以解决这些问题。
Clearly, different sources of DHA give me different benefits, and all forms have their utility.
显然，不同来源的DHA给我带来不同的好处，而且所有的形式都有其效用。
NOTE: I am assuming “high quality” DHA sources here. Cold processed and properly stored away from high temperatures and light in the case of supplemental capsules. Seafood sources that are not treated to high heat (>100C)
注意:我在假设“高质量的”DHA来源。在补充胶囊的情况下，应低温处理并妥善保存，避免高温和光照。未经过高温处理的海鲜来源(>100C)
sn-1 vs sn-2 DHA
DHA can be attached to the glycerol backbone in 3 different positions.
DHA以3种不同位置附着在甘油主键上。 图片 sn-2
image from wikipedia: https://en.wikipedia.org/wiki/File:Eie-TRIGLYCERIDE.jpg
sn-2 position DHA seems to be better absorbed into the brain. I'll let other sources explain that for me:
sn-2位DHA似乎更容易被大脑吸收。
我的解释:
① http://caloriesproper.com/vegetable-oil-fatty-acids-are-not-essential/
② http://ajcn.nutrition.org/content/61/1/56.short
③ https://hal.archives-ouvertes.fr/inserm-00958127/document
④ http://www.sciencedirect.com/science/article/pii/S0378378201002110
⑥ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894371/
⑦ http://onlinelibrary.wiley.com/doi/10.1002/ejlt.201100391/full
We have no good explanation for why exactly this is the case (that sn-2 position DHA is better incorporation into the brain), though I speculate that the more symmetrical nature of sn-2 DHA allows for more enzyme specificity due to the limited degrees of freedom for charge channeling.
并没有很好的解释为什么会出现这种情况(sn-2位置的DHA更好地融入大脑)，尽管我推测sn-2 DHA更对称的性质允许更多的酶特异性因为电荷通道的自由度有限。
sn-1 position DHA seems to be more easily processed by pancreatic enzymatic pathways, and transported within blood plasma. The implications of this I do not know. I can speculate that there is some interaction between charge interaction between the blood-borne products of sn-1 catabolism with cholesterol-sulfate in the arteries, and hence provides the oxidative signal required to maintain good cardiac function.
sn-1位DHA似乎更容易通过胰酶途径处理，并在血浆中运输。我不知道这意味着什么。我可以推测，在动脉中sn-1分解代谢的血液产物与胆固醇-硫酸盐之间的电荷相互作用之间存在某种相互作用，从而提供维持良好心脏功能所需的氧化信号。
But again, this is speculation. All I know is that sn-1 DHA tests coherent for the heart, and sn-2 DHA tests coherent for the nervous system.
但同样，这只是猜测。我只知道sn-1 DHA测试与心脏一致，sn-2 DHA测试与神经系统一致。
Questions and Tentative Conclusions
问题与初步结论
Always test. DHA from seafood, from seafood-derived supplements, or from algae-derived supplements can be “the best option” depending on the context.
频繁测试。根据具体情况，从海鲜、海鲜衍生补充剂或藻类衍生补充剂中提取DHA可能是“最佳选择”。
•What about people with so called seafood allergies? How will they respond to different types of DHA? Will they have different allergic reactions depending on the source of the DHA？
那些对海鲜过敏的人呢?他们对不同类型的DHA会有什么反应?是否会因DHA来源的不同而产生不同的过敏反应？
•How many people who “do not do well with seafood” will do fine with properly methylation support?
有多少“身体不能很好地处理海鲜”的人在适当的甲基化支持下会处理的很好?
•What about other sources of DHA? eg: eggs can contain quite a fair bit (sometimes up to 200mg DHA for 2 free-range eggs)
DHA的其他来源呢?鸡蛋含有相当多的DHA(2个散养鸡蛋含200毫克DHA)。
•What about whole algae?
那么整个海藻呢?
In any case, this is not a case where “seafood is always best”. I'm here to get the best practical result, and being open to using all tools at hand is the right approach.
无论如何，这并不是说“海鲜总是最好的”。我在这里等待最好的实际结果，而且我觉得开放性充分利用手边的所有工具是正确道路。
原文：
tanyewwei.com/blog/oct-2015-dha-coherence-testing
Timestamp:<Sun-04-Oct-2015>