@Christian Drapeau : 我认为人们对健康的关注点正在发生转变。过去，人们主要关注疾病的预防，而现在，人们越来越关注如何优化身体机能，达到最佳健康状态。这其中，干细胞扮演着关键角色。我们开发的产品旨在支持和刺激人体自身干细胞的生成，其科学依据充分，甚至可以与干细胞注射相媲美。 我最初对干细胞的兴趣源于一篇关于干细胞从骨髓迁移到大脑的论文。这颠覆了传统医学中关于干细胞只能分化成血细胞以及大脑无法自我修复的观点。这促使我开始研究蓝绿藻对干细胞的影响，并最终发现蓝绿藻可以促进干细胞的释放。 蓝绿藻中含有藻蓝蛋白、多糖和苯乙胺等活性成分，分别具有抗炎、增强免疫和改善脑功能的作用。然而，蓝绿藻的广泛疗效并非仅仅由这些成分决定，其核心机制在于它能够触发人体自身的修复系统——干细胞，从而修复各种受损组织。 在对蓝绿藻的研究中，我们发现除了蓝绿藻外，还有许多其他植物也具有促进干细胞生成的作用。我们经过多年研究，筛选出几种具有显著效果的植物，并将其组合成产品，以实现协同作用。这些植物的共同作用机制包括抗炎、促进干细胞迁移和增强微循环。 我们开发了两个主要产品：Signal和Mobilize。Signal通过抑制多种炎症通路来减少全身炎症，从而使干细胞能够更好地识别并修复受损组织。Mobilize则通过改善微循环来促进干细胞到达受损组织。这两个产品协同作用，能够显著增强干细胞的疗效。 在对干细胞的研究中，我们发现微循环对于干细胞的疗效至关重要。良好的微循环能够确保干细胞到达受损组织，发挥其修复作用。因此，我们开发了Mobilize产品，以改善微循环，促进整体健康。 在未来的研究中，我们将继续探究干细胞在心力衰竭、帕金森氏症等疾病中的作用，并开发新的产品和可穿戴设备来增强干细胞激活。我们相信，通过对干细胞的研究，我们可以更好地理解人体自身的修复能力，并开发出更有效的治疗方法。
我坚信，人们对健康的关注正在发生深刻转变。过去，人们主要关注疾病的预防；而今，人们越来越重视如何优化身体机能，达到最佳健康状态。在这个转变中，干细胞扮演着至关重要的角色。我们致力于研发能够支持和刺激人体自身干细胞生成的产品，其科学依据扎实，甚至可以与干细胞注射疗法相媲美。
我的干细胞研究之旅始于一篇关于干细胞从骨髓迁移到大脑的论文。这篇论文颠覆了传统医学的两个核心认知：干细胞只能分化成血细胞，以及大脑无法自我修复。这篇文章如同点亮了一盏明灯，促使我深入研究蓝绿藻对干细胞的影响，最终发现蓝绿藻能够有效促进干细胞的释放。
蓝绿藻富含藻蓝蛋白、多糖和苯乙胺等活性成分，分别发挥着抗炎、增强免疫和改善脑功能的作用。然而，蓝绿藻的广泛疗效并非仅仅源于这些单一成分，其核心机制在于它能够触发人体自身的修复系统——干细胞，从而修复各种受损组织。这是一种由内而外的修复机制，而非简单的症状缓解。
在对蓝绿藻的研究中，我发现并非只有蓝绿藻一种植物能够促进干细胞生成。经过多年的潜心研究，我们筛选出多种具有显著效果的植物，并将其巧妙地组合成产品，以达到协同增效的目的。这些植物的共同作用机制主要包括：抗炎、促进干细胞迁移和增强微循环。
我们开发了两个核心产品：Signal和Mobilize。Signal通过抑制多种炎症通路，有效减少全身性炎症，从而使干细胞能够更精准地识别并修复受损组织；Mobilize则通过改善微循环，确保干细胞能够顺利到达受损区域，发挥其修复作用。这两个产品相辅相成，显著增强了干细胞的疗效。
在研究过程中，我深刻认识到微循环对于干细胞疗效的重要性。良好的微循环是干细胞发挥作用的前提，它能够确保干细胞顺利到达受损组织，完成修复任务。因此，我们特别研发了Mobilize产品，旨在改善微循环，从而促进整体健康。这不仅仅局限于干细胞疗法，而是对整体健康水平的提升。
未来的研究方向，我们将继续深入探究干细胞在心力衰竭、帕金森氏症等疾病中的作用机制，并致力于开发更先进的产品和可穿戴设备，以进一步增强干细胞的激活和作用效果。我相信，通过对干细胞的深入研究，我们可以更透彻地理解人体自身的修复能力，并最终开发出更有效、更精准的治疗方法，造福更多患者。
Boost Your Biology with Lucas Aoun⋅
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02:34 预防医学应该关注身体的最佳状态，而不仅仅是避免疾病。
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03:07 人们越来越意识到可以通过优化身体机能达到最佳健康状态，这远超于仅仅避免疾病。
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03:31 支持和刺激人体自身干细胞的方法，其有效性和文献支持程度几乎与干细胞注射相当甚至更高。
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05:54 蓝绿藻的作用机制在于它能够触发人体自身的修复系统（干细胞）。
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08:07 蓝绿藻中的藻蓝蛋白是一种COX-2抑制剂，具有抗炎作用。
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08:22 蓝绿藻中的多糖可以强烈激活巨噬细胞和NK细胞的功能及迁移。
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09:12 蓝绿藻是苯乙胺的天然来源，苯乙胺与大脑健康和幸福感有关。
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10:49 蓝绿藻能够触发人体修复系统，从而修复身体受损部位。
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11:57 除了蓝绿藻，还有许多其他植物能够影响干细胞。
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13:21 来自马达加斯加的一种独特的芦荟品种是目前发现的最有效的干细胞刺激剂之一。
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13:47 西伯利亚莓在传统医学中被用于多种疾病的治疗，其作用机制可能与干细胞有关。
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15:16 通过血液样本中的干细胞数量变化来评估干细胞生成的影响。
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19:20 C反应蛋白不能作为干细胞的替代标志物，虽然两者之间存在关联，但并非总是可靠的。
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22:03 除了补充剂，禁食、低压舱和冥想也能增加血液中干细胞的数量，但效果短暂或有限。
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23:13 Stem Regen产品中的“Mobilize”和“Signal”协同作用，前者促进干细胞释放，后者抑制全身炎症。
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24:24 在阿尔茨海默病患者中，全身炎症会影响干细胞迁移到受损组织的能力。
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26:34 “Signal”产品通过抑制多种炎症通路来减少全身炎症。
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28:16 干细胞疗效受微循环的影响，良好的微循环对于干细胞到达受损组织至关重要。
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28:52 “Mobilize”产品通过改善微循环来促进干细胞到达受损组织。
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33:31 良好的微循环对于身体所有功能都至关重要。
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37:51 Stem Regen产品可以长期使用，无需循环使用。
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40:05 Stem Regen产品中使用的乳清蛋白是高度分级的，其作用机制在于提高干细胞受体的密度，促进干细胞迁移。
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43:07 Stem Regen产品几乎没有禁忌症，但“Mobilize”产品可能会影响血液流动性，需谨慎使用。
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45:01 未来的研究方向是探究干细胞在心力衰竭、帕金森氏症等疾病中的作用。
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46:28 未来的研究方向包括开发新的产品（如衰老细胞清除剂和自噬促进剂）以及可穿戴设备来增强干细胞激活。
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49:51 脉冲电磁场（PMF）可以增强干细胞功能。
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53:01 他的饮食习惯是素食主义，并注重天然食物。
00:00
The information provided in this podcast episode is for entertainment purposes and is not medical advice. If you have any questions about your health, contact a medical professional. This content is strictly the opinions of Lucas Owen and is for informational and entertainment purposes only. The references, claims and scientific information linked to any products 语法解析
00:22
are only applicable to those listeners who are based in the US. If you are outside the US, this information does not apply to you. It is not intended to provide medical advice or to take the place of medical advice or treatment from a personal physician. All viewers of this content are advised to consult with their doctors or qualified health professionals regarding specific health questions. 语法解析
00:46
Thank you for listening to the Boost Your Biology podcast. My name is Lucas Owen. I uncover the most cutting edge health information on the planet, ranging from hormones, nutrition, supplementation, fat loss, biohacking, longevity, wellness, and a whole lot more. Welcome to the Boost Your Biology podcast. 语法解析
01:10
Hello, ladies and gentlemen, and welcome back to the Boost Your Biology podcast. Today, I have a very special guest joining me in the studio. We have Christian Drapeau. Welcome to the podcast. My pleasure, Lucas. So Christian, you have pioneered an enormous amount in the stem cell space. You have released incredible products over the years. 语法解析
01:34
You're renowned for your groundbreaking work in identifying adult stem cells with over 30 years in medical research, including a graduate degree in neurophysiology. And you've authored five books. So Christian, how is the space evolving and what are you excited about at the moment? 语法解析
01:55
I mean, the space is evolving really, really well. Both the stem cell space and I would say the biohacking health optimization, however we want to call it, both of them are growing very, very well. And we're doing very well. Like we belong to those two categories, meaning that 语法解析
02:15
I think there's a shift here that quite frankly, even in 1990s, at the time I remember lecturing and telling people from stage to say, most people think about health when they have a problem. But when they don't have a problem, the best thing that we have to do is preventive. 语法解析
02:34
But if you do preventive medicine, the focus is on preventing the problem. You don't reach optimal health by just preventing the problem. You just don't have the problem. 语法解析
02:45
So I was seeing this huge gap in between optimal health and just being in a place where you don't have a problem. And I think that this is the area now that is really growing super fast, where people realize we have a machine, the body, and there's a way to really make this body works optimally, which is far beyond just not having a problem. 语法解析
03:07
And I think that area now is just really exploding in the marketplace. And with stem cells, I mean, we're really right in the eye of the storm, you know, with that kind of approach. And on the stem cell side, stem cells are more and more recognized. More and more people have heard about stem cells or seeking stem cells. And in this whole development, what we have developed, which is supporting and stimulating the body's own stem cells, 语法解析
03:31
from a purely scientific standpoint, is really just as strong and just as documented, to an extent, I would say almost more than stem cell injection. So this is moving forward. It's gaining more and more recognition. So, I mean, no complaint. Everything is moving very well for what we're doing. Yeah, fantastic. And in terms of, I mean, I'd be curious to know about your first initial interest in the stem cells. Like, do you remember the first day or the first… 语法解析
04:01
when you actually discovered them or researched them. Absolutely. So we had all, anybody that studied medicine had learned that stem cells from the bone marrow are precursors to blood cells. So any med student knows that. So for me, it was one day when a colleague sent me an article and quite frankly, when I received the article, I did not click. It didn't click in my brain. That article sat on my desk for about like three months. 语法解析
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And then one day I'm cleaning my desk and I come across this paper again. And now… 语法解析
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Reading the title, it kind of triggered a light bulb. And the title was Turning Blood into Brain. It was a study talking about the observation of stem cells going from the bone marrow to the brain. So two immense, like huge dogmas of traditional medicine were broken by this article. Number one, stem cells can only become blood cells. And that study showed a stem cell becoming a brain cell. 语法解析
04:59
Second, in neurophysiology, we learned the brain does not repair. And here's a new neuron that is derived from a stem cell from the bone marrow. 语法解析
05:08
So, so suddenly in that moment, the past five years of research, trying to explain how this blue green algae was working, which is because we had a blue green algae with whom I met cases of people who reversed or significantly improve problems associated with the heart, the pancreas, the lung, the liver, the brain, the skin, so many different aspects of human health that we had no explanation, no understanding how this plant was working. When I read this article, I, 语法解析
05:37
Very quickly. I mean, on that day, the math that happened in my mind was, wow, that means stem cells can become brain. So that means they can become everything else. So that means they must be the repair system. What if that plant triggers stem cells from the bone marrow? It would explain all the cases that we had seen from that moment forward. 语法解析
05:54
Then I started to dive in the scientific literature to first see, is this idea even making sense? And the more I read, the more this idea made like more and more sense. It was very solid. There was tons of studies out there to really support this sort of new thought. And we finally acquired a flow cytometer to count some stem cells in our own blood. And then we took it before, we took a sample before and after consuming this blue green algae, and we discovered that it was a stem cell mobilizer. So, 语法解析
06:23
That was like what led us to that discovery. But it all started on that day when I came across this article and it triggered the whole thought process of, you know, maybe stem cells are really something relevant in the body. 语法解析
06:34
Yeah, incredible. And let's get stuck into that blue-green algae. I mean, do you want to sort of explain to my listeners what that's called and maybe some of the other unique benefits of this particular ingredient? So blue-green algae is a class of eukaryotes. 语法解析
06:52
that are basically, sorry, prokaryotes, that are basically include like spirulina, nostoc, there are a number of species, but while they're all the same, they all contain phycocyanin, which is the blue pigments present in blue green algae, they're also all different in some ways. 语法解析
07:09
Good work has been done on Nostoc for its effect on the digestive system. And spirulina is well known. So the one that I was working with was a blue green algae growing in Klamath Lake in Southern Oregon. The species is called Athanizominon flos aqua, so AFA. 语法解析
07:25
So when I was hired by the company selling this product in 1995, the benefits that were the most commonly reported were an effect on inflammation, an effect on the immune system and an effect on the brain. Like half of the consumer would report a sort of enhancement of mental clarity, mental energy, mood elevations. People were feeling good. It was almost like to some people like addictive. 语法解析
07:48
So my job was to find the active compounds and mechanisms of action behind these three main benefits. So what we have discovered very quickly is that as a source of phycocyanin, phycocyanin is a COX-2 blocker. So that's the mechanism of action on inflammation. 语法解析
08:07
We found that the polysaccharides is a very strong activators of macrophage, very strong activator of NK cell function, natural killer cells, and also NK cell migration. So NK cell will patrol in the body to find virally-infected cells 语法解析
08:22
or cancer cells and will kill them. So their job is outside of the blood circulation. So they need to be able to migrate into tissue and do this sort of scouting work. So by having a polysaccharide that stimulated their migration, it was something, even to this day, it has not been properly exploited. It's an amazing product for immune support and immune boost. 语法解析
08:43
And then we discovered that it's a natural source of phenylethylamine, which is PEA, which is known in chemistry as being the molecule of love, the molecule of joy. Anytime you're absorbed, let's say you're painting, you do something you love. You're absorbed in it. You're not hungry. You're not distracted by noise. Your financial problems were there yesterday. Don't worry, they'll be back tomorrow. But right now, for some reason, they're not bothering you. Everything is fine. You're just happy. Your brain is making PEA. 语法解析
09:12
If you're deficient in PEA, we can measure that in the urine, and it's a way to diagnose ADD in kids and ADD in depression in adults. So it's a molecule that has a real involvement here in brain health, if you want. So by being a source of PEA, AFA, it explained all the benefits that people had reported in terms of concentration and a sense of well-being. 语法解析
09:35
So it's as I'm doing all of this that I came across people who reported complete reversal of something like insulin-dependent diabetes, recovery from heart attack, recovery from strokes, recovery from severe emphysema, lung damage, liver failure. 语法解析
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So Alzheimer's. So you look at all these conditions and that means this product was doing something that we could not explain on the basis of its content in in phycocyanin, polysaccharide and PEA. And not only we cannot explain them, but to me at a deeper level. 语法解析
10:09
The mystery was what was this plant doing to help someone's liver, someone else's pancreas, someone else's heart, someone else's brain, someone else's lung. It seems to be doing everything in the body. 语法解析
10:21
And I remember in those days, people would sell this product and they would say, this blue green algae will do to your body what your body needs. For a scientist, that was so fruitcake. I was telling people, stop saying this. Like, it's so ridiculous. This plant will do to your body what the body needs. I thought it was like a ridiculous statement. And yet after discovering the role in stem cells, I would say the broadest way to summarize what it is 语法解析
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is that this plant will trigger your repair system and your repair system will repair whatever is broken in your body. So it's going to basically promote the repair for whatever is the problem in your body. It was actually a very accurate way of reporting what this plant was doing. So that's what I can go deeper, but that's what I can share about this blue green algae in climate lake. It was not, and it is not the strongest plant that we have studied. It's actually one of the lesser effective plants 语法解析
11:18
in terms of stem cell effect. But it's the one with which we discovered the whole phenomenon. 语法解析
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Yeah, so it formed the basis of then like, okay, what else is out there? What else can we combine it with to synergize and enhance? And you guys have done a fan or you have done a fantastic job at actually formulating products that incorporate the blue-green AFA alongside. Did you want to maybe talk about some of those other ingredients that you think sort of stack really well or combine really well with that? Yeah, so the moment that we discovered the effect of AFA, this blue-green algae on stem cells is 语法解析
11:51
Immediately in my mind, it cannot be that there's only one plant in the world having an effect on stem cells. 语法解析
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Like we evolved in symbiosis with the environment and just like there are many plants supporting the immune system, there has to be many plants supporting the repair system. So how do you find them? It's very simple. Something that is going to support the repair system because when stem cells are released, they will go to the organ that is damaged because it's the repair system. So these are plants that would have been associated historically with a broad variety of benefits. 语法解析
12:23
So I started to look at these plants, things like goji berry, medicinal mushrooms. So we tested a lot of those and we found some benefits, some effect on stem cells, but nothing that was like earth shattering. It was just confirming the fact that there are many plants having an effect on stem cells. 语法解析
12:40
So over the years, we tested probably like a dozen, maybe 18 of these plants. And the top five is those that we find now in stem region release. So the one that I came across that were really amazing winner. So one is a unique species of 语法解析
12:55
aloe coming from Madagascar. So we trademarked stem aloe to really indicate what it's doing. But of 65 species of aloe, it's the only one that was used in Madagascar to develop an indigenous product there by the Malagasy people used for centuries for all kinds of health conditions. So I went there, we collected some of that aloe, we derived that ingredient, we tested it, and it's so far the strongest ingredient that we have. 语法解析
13:21
Another very interesting one is Sibucton berry from the Tibetan plateau or from high altitude. So in traditional medicine, Chinese medicine, Mongolian medicine, Sibucton berry has been used for disease of the lung, disease of the heart, cardiovascular system, diabetes or pancreatic function, and to boost the repair from bone fractures or injuries to the skin. So you look at this spread and it's almost like screaming at you stem cells. 语法解析
13:47
So I went, I met with a farm on the Tibetan plateau. We derived an extract, we tested it, and we saw a very good response on stem cells. 语法解析
13:56
So we have in that fashion tested as well, Ficoidan from certain seaweed, Panaxnodo ginseng, so the original Chinese ginseng. These are the top five plants having so far the strongest response on stem cells. And they all work. They share some mechanism of action, but across these five plants, we have three main mechanisms of action, which means a great synergy by using these plants together. 语法解析
14:23
Christian, out of curiosity, when it comes to measuring and analyzing the impact on endogenous stem cell production, what methods or methods are being done to do that process, to undergo that assessment? I mean, what we have done, because you can quantify the number of stem cells in the bone marrow, but it's extremely difficult to do because it's invasive. So if you want to do this study on humans, you 语法解析
14:49
and the human or the people don't get any benefit, they just get, you just give them 250 bucks, you know, for them to provide a puncture of their bone marrow, it doesn't go through the approval process. So it's a very difficult study to do. We have tried it. We were very close to be able to do it. It's very difficult. So what we have relied over the years and on a simple blood draw, and we count the number of stem cells in the blood circulation. 语法解析
15:16
So we are using a machine, a device called a flow cytometer, which essentially when you take a blood sample and you inject that blood sample in the flow cytometer, all the cells will line up one behind the other one and they'll go in line in a tube and they will pass in front of a laser behind which there's a photosensitive plate and it's going to measure different properties of that cell. 语法解析
15:42
A real good flow cytometer today will have more than one laser with different colors. So what you do is that, let's say you incubate your cell sample with antibodies specific for markers of stem cells or markers on non-stem cells. And you attach to these antibodies a green tag, a red tag, a blue tag, yellow, green, all kinds of colors. So when the cells now pass in front of these lasers, 语法解析
16:08
The photosensitive plate can measure their size, their luminosity, each type of cell has its own innate luminosity, and what kind of markers are attached to that cell. So we normally use two or three stem cell markers and a few non-stem cell markers, so you can use inclusion and exclusion factor to basically say that cell was a stem cell. 语法解析
16:30
or amazenchymal stem cells, or endothelial progenitor cells, or small stem cells. So we can even define what kind of stem cells it was. And by this process, we can count how many stem cells and what kind of stem cells were in your blood before and after taking whatever material that we want to tell. 语法解析
16:48
And we need to do this on two different days because you have your own circadian cycle, like between 5 a.m. when you have peak number of stem cells to 5 p.m. where it's the lowest. So you have a decline in number of stem cells. So we determine your circadian cycle on one day using a placebo and the 语法解析
17:06
blinded and on the next day or in another day then we give you the plant extract and then we basically subtract from the response that we have your circadian cycle to really see how many more stem cells were put in the blood circulation after taking these plant extracts so that's the process that we have that we that 语法解析
17:25
And this exact process doesn't sound like the average person can just go to their local doctor and just get a blood test. We don't even have that level of accessibility, right? This is high level. The flow cytometer, is that what you call it? Yeah, flow cytometer. 语法解析
17:43
I mean, it used to be when we started our research. So in Oregon, there were three flow cytometers in the entire state. So we're in nine. We are what in 2001, three flow cytometers in the state. We had two of them. 语法解析
17:57
One of them was at the University in Corvallis, and that was it. Now it has become more common. It is widely used in cancer centers, anywhere where they need to count how many stem cells you have in your blood, because it's one of the parameters to assess your need for bone marrow transplant after chemotherapy or radiation therapy. So you go to most cancer centers, they have a flow cytometer. Some places where they do stem cell injection will have a flow cytometer if they do good quantification. 语法解析
18:24
quality control on the stem cells sample that they use to inject. Because if you're told that you have 100 million and you rely on the label, oftentimes that's not what the test tube has. So some of these clinics will do their own quality control. But outside of that, no clinic where you go for just a blood test will have a flow cytometer. So it's not something you can get easily. It exists. It's out there. It's a very well-known technique, but it's not accessible if you just want to know how many stem cells you have. 语法解析
18:52
Are there any other blood markers that you guys have identified as like when stem cells go up in the blood, it also appears to impact this biomarker, like, I don't know, C-reactive protein or any other? Yeah. Yeah. Yes and no. I mean, the answer is yes, but to an extent, I don't think they can be reliable. What I mean by this is that the most, probably the most potent anti-inflammatory biomarker 语法解析
19:20
The most anti-inflammatory factor into your body is stem cells. So stem cells are called by a tissue that is releasing inflammatory signal because these are SOS. They're communication signals to tell the stem cells that's where the problem is. These molecules should be localized. Inflammation should be localized to tell stem cells where the problem is. 语法解析
19:44
inflammation tends to be destructive to a tissue. So when the repair system is coming in that area, stem cells are migrating in the area, the first thing that they do, they start to release a bunch of compounds that are anti-inflammatory. So they suppress inflammation because you cannot get repair and inflammation at the same time. Just think about it. The last time that you had a cut, 语法解析
20:07
On the first few days, it's very sensitive. And when you see that your cut is actually starting to repair, sensitivity is gone. Inflammation has gone down. 语法解析
20:16
But it's because repair has started to kick in and your stem cells are starting to play their role of repair. So stem cells are extremely anti-inflammatory. So if your body is not overwhelmed by systemic inflammation, if you have some level of systemic inflammation caused by an area that needs repair, when that area repairs, you will have a reduction in systemic inflammation. So we have seen in a lot of our studies when people do better with 语法解析
20:45
whatever it is that we're studying at that time, we see a decline in C-reactive protein. But if a person has reached too significant of a level of systemic inflammation, the flip side now is that your stem cells are kind of 语法解析
21:01
in their ability to see where the inflammatory signal is coming from. They're there in your bloodstream, but they cannot really fully do their work of tissue repair, which is why we develop the product signal. So the stem cells are there. You count them, but the inflammation cannot be used as a surrogate marker for stem cells. So there is a link there, but it's not always right for them. 语法解析
21:29
So Christian, in terms of like the – I want to learn more about like – because my audience will obviously want to understand – 语法解析
21:37
How can they actually stimulate stem cell production without the use of supplements? We'll get to the amazing products that you formulated. But from your initial research, what were some of the methods used to actually increase the body's production naturally? Well, there's not a whole lot that is known. Of what has been documented, fasting for more than three days will increase the number of stem cells in circulation, but it's transient. 语法解析
22:03
Yes, you've put more stem cells in circulation, but it goes back to baseline. So it's not by itself a strategy. And you cannot fast three days every day. So it's limited. But that's one way to put more stem cells in circulation. Hypobaric chamber will put more stem cells in circulation. And something that has not been published, but a scientist reported that in an interview that she did, Dr. Taylor. But she's a really good stem cell scientist. 语法解析
22:30
So I don't doubt what she said. I've simply never seen the data meditation. So if you take a good meditator who meditates for 20 to 30 minutes, you can quantify after more stem cells in circulation. So these are the ways to put more stem cells in circulation. 语法解析
22:46
Okay. So then let's look at the difference. So you've obviously, Stem Regen has, you've got some incredible products, right? You've got the Mobilize, you've got different Signal. Just talk to us about how you actually decided to combine them, to structure them out so that they synergize really well together. Okay. Let's go back for a moment to what we talked about before. Inflammation, systemic inflammation, their effect on stem cells. 语法解析
23:13
Some 20 some years ago, we had access to a population of people with Alzheimer's. So I think we're probably 2002, 2003. And my thought at the time, so we're early in the process here. So I'm already thinking if stem cells are the repair system, the people who develop age-related disease must simply have fewer stem cells than other people. So let's go and test in that population. We should find fewer stem cells in people with more advanced Alzheimer's. 语法解析
23:40
And it was very interesting because this is true for just about any age-related diseases, except Alzheimer's, where the picture is a little bit more complex. And now some group have published on this, but we saw that in that study, meaning that, yes, there's a link between the number of stem cells in circulation and the advancement of Alzheimer's, but not in everybody. 语法解析
24:02
We did have some people with very advanced Alzheimer's with a lot of stem cells, but when we looked more closely at these stem cells, they had lost the receptor that they need to respond to the inflammatory signal. And we found that the link between the degree of Alzheimer's and the other parameter was C-reactive protein. 语法解析
24:24
So these people actually had a very, very high level of systemic inflammation. So in a nutshell, you've got a lot of problems in the body. The brain is calling for repair. Stem cells are being released, but the systemic inflammation is numbing stem cells and removing their ability to be able to migrate 语法解析
24:43
at the area where normally the inflammation is being released to go and repair that tissue. So the stem cells are there, but they're no longer able to go where they need to repair. So from that point on over the years, I've developed a number of products that I have tried in small groups that I sent to doctors to see, do you see a benefit? And it became very clear quickly that these two were really an amazing duo. 语法解析
25:07
So you release your own stem cells, but at the same time, you suppress systemic inflammation to basically allow stem cells to see where the inflammation is coming from. It's a little bit like you walking in a big house and you see smoke everywhere. And I tell you, okay, put water on the fire, but you don't know where the fire is. There's too much smoke. 语法解析
25:25
So let's first reduce inflammation, remove some of the smoke, and you can see where it's coming from. And right now in the whole world of stem cell injection, many clinics will tell people, stop taking ibuprofen, stop taking anything for your inflammation, because the stem cells need to see where the inflammation is coming from. And the reasoning is not faulty. 语法解析
25:47
The logic is there, but overall, I think it is faulty because in reality, you will never completely shut down the site of inflammation. It will still be there. You will reduce the noise in the background, and you will then allow stem cells to better see where the problem is. And that's how we develop signals. 语法解析
26:06
Signal is a blend of many different types of plant extract that have all been documented to inhibit one or two or several different pathways of inflammation. So the product collectively will block COX-2, will block 5-LOX, will block the secretion of a lot of interleukins and other inflammatory cytokines. And then we have bromelain that will digest whatever has been already generated. So it really suppresses 语法解析
26:34
everything that is inflammation in the body to help stem cells guide them to see where they need to go. So that's where it came from. So the general concept or idea behind these two new products, Synil and Mobilize, is that we have, and it really mirrors what people have seen, clinics have seen with stem cell injection. And I'm summarizing here the statistics. You go to roughly about any clinic. Some people will claim that their numbers are much higher than 语法解析
27:03
I somewhat doubt it, but nevertheless, the number is not relevant. It's the concept. 30% of the people getting a stem cell injection will say, it changed my life. It was amazing. 30% will say, oh, I saw great improvement, but it was not everything that I was expecting. 30% will tell you it was a waste of money and a waste of my time. And we see something of the same nature with stem regen release. We have probably 75% 语法解析
27:31
return customer or people who come back and say it really had an amazing impact. It's huge in terms of statistics, you know, of benefits, but it's not everybody who get the benefits that we thought that they would have. So we need to understand that the power of stem cells in a test tube, you can make stem cells become a full beating heart in the test tube. It is unbelievable the raw power of stem cells. 语法解析
27:55
Why are they not doing this in a person? We release their stem cells. They don't seem to have an effect. I think there's two reasons. One, they cannot see where they need to go. There's too much inflammation. We need to suppress inflammation. If the place that needs repair is a chronic situation, that means that locally the microcirculation has been compromised. 语法解析
28:16
You don't have good microcirculation. A stem cell can be 20 microns. The fine capillary is 12 microns. Something needs to be done for these stem cells to have access to that area. You may have them in your bloodstream, but if they don't have access to the damaged area, that means that area is deprived of the power to repair. So… 语法解析
28:36
Then we develop Mobilize. So Mobilize is natokinase to make the blood more fluid so you get better entrainment. Nitric oxide producer to dilate arterioles so that you feed more liquid to capillaries, but for capillaries to be able to extend 语法解析
28:52
you need to have a good environment, a flexible, elastic environment. So we have bioflavonoids and plant extract like ginkgo, gotu kola that have been well documented to help this environment of capillaries. And for cells to really slide inside these capillaries, we need to reconstruct a healthy glycocalyx. So we have polysaccharides that help rebuild this glycocalyx. 语法解析
29:14
So we haven't mobilized the four technologies to really maximize capillary circulation. So now you take stem region release, you release 10 million stem cells within two, three hours. You take that with mobilize, which within two, three hours will have improved and opened the microcirculation and signal will have reduced the systemic inflammation within that timeframe. Both signal and mobilize will also have more of a long-term effect 语法解析
29:41
So their effect will accumulate. Some of their effect will accumulate, let's say, over 30 to 60 days. So all along, you kind of boost the impact of the stem cells that you're releasing. So that's why we developed this package. 语法解析
29:54
Incredible. With the mobilize, you mentioned microcirculation being a crucial component. I think that's just in general, extremely important for general overall health. As we age, we know that circulation declines, nitric oxide production does tend to go down if people are not eating enough polyphenols and flavonoids in their diet. 语法解析
30:18
Just talk to us about, is there a role there with the nitric oxide beyond just blood flow? Is there a link there with stem cells at all or not so much? Stem cells and nitric oxide? Yeah. Is there a link between those two? I mean, I know that some studies have reported that nitric oxide can also help mobilize stem cells. 语法解析
30:41
uh to to what degree i don't know but it would be it would be to me very simple logic the moment that you dilate capillaries then you promote more blood flow you have more a greater chance to entrain stem cells and make them detach from the bone marrow so it would have its logic so it can certainly do it um but but to me going back more to what you were starting earlier in your question 语法解析
31:05
I remember my class of cardiac physiology and the whole part of hemodynamics. It was a fascinating part of my training in physiology because we were studying how when blood go, think of pipings, when blood go from a big pipe and it forks into many smaller pipes that fork again. And if you have, let's say, deposit of fluid, 语法解析
31:28
fat or calcification at the entrance of one of these vessels, it creates turbulence at the entrance of that vessel. Turbulence means, look at turbulence when a river gushes into a small lake and you get that turbulence. And oftentimes you throw a piece of wood and it gets caught back and trapped into these vortices. So my point is that 语法解析
31:50
a vortex at the entrance of a tissue could be an absolute barrier for a cell to enter that tissue. When the cell comes in, it bounces on it and it continues. So that area where you've got all of these irregularities in your capillary bed could be an area that has no access to stem cells. 语法解析
32:14
So with the, you mentioned there, like a lot of, a big percentage or a big portion of the population would have these micro deposits of like plaque or there's just so many different like reasons why many people actually have dysfunctional blood flow. And most of the people that are listening to your podcast are already taking a lot of supplements, NMN, CoQ, whatever, a lot of supplements, right? 语法解析
32:41
And these supplements, for the vast majority, they will do their work when they get into the cells. To get into the cells, the blood must carry those components through the fine capillaries. So that is a part that, and that's where I was going with this explanation, is that that's one part that is virtually absent of the whole language about, 语法解析
33:02
about general health and health optimization, biohacking, everything is that you go to your doctors, they take a blood sample, they tell you all the great things about your blood, but if that blood doesn't reach your liver, your pancreas, whatever it is, it's pointless. 语法解析
33:15
It is irrelevant for the area where you have the problem until you reopen the proper blood micro circulation in that area. So to me, we developed the product to support or maximize stem cell circulation, but put stem cells aside. 语法解析
33:31
You need good microcirculation for everything in your body. So just start to increase microcirculation with a product like Mobilize and just observe everything else that happens in your body. Faster recovery. All the supplements that you're doing right now, you maximize them because they reach everywhere where they need to go. So to me, it's a huge part of optimal health that is not really talked about. 语法解析
33:55
Christian, in terms of your formulating experience, I know you've studied many different ingredients over the years. Has that been just purely like an independent process by yourself or you've sort of 语法解析
34:06
you know, worked with other formulators or other scientists to sort of select ingredients? I have at times been asked to do a product with a specific outcome, but for the most part, I'm, I'm, it's just the way my brain is wired. I'm like, I like innovation. I don't like to just do something that has been discovered. No, no judgment on people who do that at all. It's just my motivation comes from 语法解析
34:32
doing something that is new. So I've really mostly been drawn to ingredients that are either unknown or have been documented, but they're not present in the marketplace. So most of what I've done has been with like new plants. And I know that you're involved a lot in testosterone support. So we could talk about that because I'm, I'm, 语法解析
34:51
trying here to develop it's a new plant but the plant is not new the plant is known but it's nowhere anywhere on the marketplace and if you chew the peel of that fruit it makes your body secrete more testosterone it will be a fascinating product on the marketplace uh you're you're now testing my knowledge whether or not i've researched this don't know it i mean you might you'll be the first is it a is it a type of fruit is the peel the peel of a fruit 语法解析
35:22
Is it a, not like a citrus, not like a mango? No. Like a berry? No. Not a berry. Jeez. Okay. It's a secret. I don't want to say it. So we'll talk about it. Yeah. Okay. 语法解析
35:38
All right. I love that idea. Look, I'm also the same as you. I love understanding mechanisms and I also love like hunting for the treasure. It's like you're trying to find that hidden ingredient or that hidden herb that nobody really knows about that you really want to just bring to the forefront. I mean, you've done that pretty well with some of the other products like the… 语法解析
36:01
You've got the Terminalia chibula. Do you want to just talk about that one? Because I don't think many of my audience would be familiar with what that herb actually is. They probably are. They probably know it under the name Haritaki or probably under the name of Trifala. 语法解析
36:21
So Triphala, which is like the go-to overall harmonizing blend in Ayurvedic medicine. And it's three berries. One of them is Aritaki. So Terminalia chibula. I think you have Terminalia chibula, Terminalia. There's another Terminalia. And, oh, man, I'm forgetting the three. But anyway, there are three herbs. 语法解析
36:42
Amla, amla, terminala chiboula, and another terminala, it's another fruit. So there are three berries that are dried and blended together. It gives you three phala. And terminala chiboula has been documented for many, many benefits, but… 语法解析
36:56
And among other things, we tested it for stem cells. There is a stem cell effect, but it's not very strong. It's one of those plants that has been associated with many kinds of benefits. We tested it for stem cells and we saw a small effect, but it has been well documented for its effect on inflammation and five locks. 语法解析
37:15
So to inhibit 5-LOX, which is one pathway of inflammation, we blended it with phycocyanin, which is a blocker of COX-2. The idea was to address inflammation through all the different pathways that we could. So that's why terminology BULA is in signal formulation. 语法解析
37:32
In terms of the dosage recommendations and like cycling protocols, are these products intended to be used on an ongoing basis or do you advise like temporary sporadic breaks from these particular ingredients? My approach to it, cycling is not something that… 语法解析
37:51
in my brain that I've really paid attention to over the years, over my life. So anything that I do, I pretty much, if it's good for me, I tend to do it every day. So Stem Regen Release or any of its predecessors since early 2001, I've taken every day of my life. So I don't cycle on these products. 语法解析
38:13
But if somebody wanted to cycle, I don't really see any problem with it because stem regen release is more powerful than anything else that I've done before. If you release 10 million stem cells with two capsules average, and then you do this every day for a month, you've released 300 million of your own stem cells. If one injection of 100 million stem cells… 语法解析
38:36
that you get when you go somewhere for, let's say, $15,000, if that is meaningful for you, then $300 million must also be meaningful. So I'm thinking you could do this for a month and in your 30s, do this twice a year. In your 40s, do it at the change of season. In your 50s, do it every other month or start to do it every day. There's a point you 语法解析
38:59
you will have a greater impact by really doing this every day. But when you're earlier in your life, yeah, maybe you can totally cycle. You may not need to do this all the time. I noticed that one of the ingredients in the Stem Regen release was the highly fractionated colostrum. 语法解析
39:18
Colostrum is a game-changing ingredient for gut health. I'm a big, big, big fan, specifically for histamine issues, leaky gut, but 语法解析
39:30
Just talk to us about colostrum. I mean, that's like documented to have many, many benefits. It's an amazing product, but I just want to like here specify colostrum, bulk, good colostrum will go anywhere between $30 to $60 a kilo. The colostrum that we're using is $800 a kilo. 语法解析
39:50
So it is, that's why we call it highly fractionated colostrum. How else can you name it? You know, but it's really, it's a tiny, tiny, tiny fraction of colostrum. And that's the one that we tested for its effect on stem cells. 语法解析
40:05
And the reason is that the vendor of this product was a good friend of a very good friend of mine. And at some point, this friend was telling me, you know, they have like they have a lot of benefits, like very similar to what we had with the blue green algae. So this was a long time ago. And so I decided, like, let's give it a test. Let's test it for its effect on stem cells. And we saw a result that was completely different from what we normally saw with a lot of these plants that trigger stem cell release. We saw a drop. 语法解析
40:34
in the number of stem cells in circulation. And we had also seen that with mushrooms, goji berry. So by the time we knew what it was, and it's essentially is that it triggers an increase in the receptor, the density of the receptor that stem cell use to identify the tissue in need of repair. So that means the stem cells now are more responsive to a call coming from a tissue. So they disappear from the bloodstream more rapidly. So in a blood test, you see that after 语法解析
41:02
30 minutes as a drop in the number of stem cells. So the moment that we started to see this phenomenon, to me, it was kind of clear. Repair for stem cells means stem cells must leave the blood circulation, get into the tissue and repair the tissue. So the passage from the blood, the migration from the blood to the tissue is essential. So if we have a product that support that, it's bound to help the overall repair process. 语法解析
41:26
But I cannot really talk about it in terms in scientific publication because that step of migration has not been very well documented. Because until you have a drug that does that, then nobody in the pharma will study this. And we don't have enough money to really study this fundamental process. But it's obvious, you know, if you're in a room and there's a door and now you're inside the room, it's because you went through the door. 语法解析
41:49
So I don't have to measure that you went through the door. You went through the door. So if a stem cell gets into tissue and repair, it had to migrate across the capillary wall. So if I have something that boosts that process, let me add it to the plant extract that stimulate the release. And then I'm going to boost the overall process of tissue repair. So now I started to combine my stem cell releasers with my stem cell migrators. And the top two that we had was one, three, uh, 语法解析
42:18
beta-glucan and this highly fractionated colostrum. So that's why we added it to the product. Incredible. Incredible. Yeah, I'm a big fan of that ingredient. What about in terms of any potential contraindications for any of your products? Of course, my audience will want to know, should people be sort of careful with any of the products? There is none with stem regen release, really. It's something… 语法解析
42:44
I mean, all the years that we've had these products, really, we don't see any kind of issue. When we start to get with Mobilize, it has a chance to change your blood fluidity, but it does it naturally. But it can impact, if you're taking an anticoagulant or you're taking something that is going to make your blood more fluid, it can accentuate blood fluidity. 语法解析
43:07
So you can now look at it in different ways. You can say, oh, it's interacting with my drug, so I need to stop to take it. Or you can say, it's achieving what I want, which is a blood that is more fluid, but it does it naturally, so I prefer that. And let's try to wean myself with your doctor of these anticoagulants. This is the person's choice with their doctor, but it can influence blood fluidity. Okay. 语法解析
43:33
Outside of that, nothing now comes to mind in terms of any other types of side effects coming from these ingredients. Good to know. In terms of the future, Christian, I mean… 语法解析
43:49
Now, Stem Regen has how many different products, like four, three? Yes, four. So we have the Stem Regen release and we have a sports version of it, which is really we added one ingredient that boosts repair of joint, muscle, tendon, ligaments, which is what anybody doing intense physical activity need after a session of intense activity, you want to repair faster. So you release stem cells and you promote stem cell differentiation into these different tissue. And it is NSF certified, but they're doing the same thing. 语法解析
44:18
putting more stem cells in circulation for tissue repair. And the other two mobilize and signal to suppress inflammation and boost microcirculation. Yeah. And in terms of, I guess, the future direction, I mean, what area are you excited to see more research on in particular in the field of stem cells? 语法解析
44:39
Well, right now we are doing quite a bit of studies. So we're starting a number of studies and continuing a number of ongoing studies. One is on congestive heart failure. One is on Parkinson's. And we don't want to show stem regen will have an impact on heart disease and Parkinson's. What we really want to show is to say we have a product here that will make your body release more of its own stem cells. 语法解析
45:01
Once the body has released its own stem cells, your body can utilize these stem cells for tissue repair. And to really understand the extent of that healing power that your body has, 语法解析
45:14
Let's look at the role of stem cells or the power of stem cells in conditions where science normally cannot do anything. If you have congestive heart failure, we will give you better blockers to protect your heart, hypertensive medication to reduce blood pressure, so the pressure on your heart. We give you different elements to try to modify the environment around your heart, but we absolutely never, ever address the main issue, which is 语法解析
45:42
There's nothing to do to address this. So we have a study on congestive heart failure. And so far, the study is ongoing. But on 10 patients with chronic stable congestive heart failure after six months, they've all recovered normal heart function. We have another one in Parkinson to show here's the brain that is not supposed to repair. See what your body can do when it has more stem cells. 语法解析
46:04
We're preparing one on COPD, long issues, liver failure, colitis. So we're working with different conditions here just to show here's what your body can do with more stem cells. So we're going in that direction. We're developing, we're working on two other products, senolytics, autophagy, but also instruments that can be like wearables that can have an effect on the stem cells that you have released. 语法解析
46:28
Like there's certain wavelength that if you shed that on your blood vessels, it's going to activate certain stem cells that have been mobilized and they're now in your bloodstream. So we're working on these kinds of wearables and also wearables in terms of PMF. PMF, pulse electromagnetic frequencies, is amazing for overall health. I mean, tons of studies have been done on it. 语法解析
46:50
And what is emerging now in science is that one of the main mechanism of action for PMF is that they actually boost stem cell function. So if you release stem cells and you couple that with PMF, then you boost both the PMF and you also boost the impact of the stem cells that you've just released. So these are directions that we are taking. In the whole world of stem cell research, some areas where there's good development right now is, for example, I take your own stem cells. 语法解析
47:17
I identify what are the genetic weaknesses, and then I inject a corrective gene that is going to compensate for that weakness. I reinsert these stem cells in your body. They go into your bone marrow, and now they correct. Now you have a new strain of stem cells, your own stem cells. 语法解析
47:35
With a corrective gene. So if that gene is a weakness, whatever it is, then those stem cells, as they continue the day-to-day process of tissue repair, tissue maintenance, tissue turnover, you're slowly replenishing your tissues with cells that no longer have this genetic deficit, if you want. 语法解析
47:53
And that started. It's very early, very, very early. That is extremely like, to me, that sounds like such a sophisticated thing to achieve. But he doesn't surprise me anymore because, you know, the technology we have nowadays, the scientists, like we can do basically anything we want. 语法解析
48:12
Like with the right bright minds, like it's just incredible to see that space. But you mentioned the wearables. So you're saying like there's certain – are you saying there's like pulsated frequencies or is it sound waves or is it vibration? No, it's electromagnetic. So it's like electromagnetic. So a device that – 语法解析
48:32
that releases electromagnetic frequencies will do this and will have an effect on a radius of probably, let's say, maybe like a foot. But it really depends on the power of it. If only 5G did that to our bodies. I mean, that's a good question. That's a good point that you're saying there because oftentimes people are confused. And it's very interesting because, okay, let's take oxygen. Oxygen is good for your health. 语法解析
48:57
But if I were to put you into low oxygen, super high oxygen, low oxygen, it would like completely destroy you. At some point, you're in deep hypoxia and another time you're in full oxidation mode. You'd be destroyed. But if I just give you pulse of a good concentration of oxygen, it can have hyperbaric chamber. It can have a great impact on your health. Electromagnetic frequencies are the same. 语法解析
49:22
The type of frequencies, the way that they're pulsed, what frequency, the regularity of that pulse, the magnitude of that pulse. Like there's a way of organizing these waves that we have seen as a very positive impact on your body, which is not what you get when uncontrolled electromagnetic noise, if you want, coming from your walls, coming from Wi-Fi. This is a completely different source. It's the same thing, but it has a completely different impact on health. 语法解析
49:51
Yeah, I like to look at it as like invisible pollution. That's just like, yeah, when it's uncontrolled and it's like in the wrong frequencies and the wrong dosages can be detrimental. But I mean, something that's sort of come up recently, and this is something that I'm personally really excited about is the wearable technology space, the biosensors that are being released. So obviously we have the well-known continuous glucose monitor. That's very well, you know, a lot of people know about that. 语法解析
50:19
I even brought up on another podcast, I'm excited to see whether or not we have the opportunity and the ability to create a continuous testosterone monitor. So like a CTM, I haven't seen this being developed anywhere, but if it was, I would invest in it immediately. Like I would be very interested. What would be the value of it knowing that testosterone, its effect is not immediate? I think the value would be let's like… 语法解析
50:46
analyze the effect of different supplements, different peptides, different training modalities, different foods. And we can see in real time the spike in testosterone or perhaps even I know clients that I've worked with that they've had a really great week financially in their career and we did their blood work and their testosterone was like way above. And I'm like, okay, that makes sense. Yeah. 语法解析
51:12
I mean, I love the blood glucose monitoring. I only did it once. I'm not very heavy in wearables, but I did it once. And I was, I mean, I was amazed by what I discovered. And the main discoveries was the extent of these glycemic excursion after like an orange juice. 语法解析
51:33
Like little things. And then understanding that physiologically, anytime you have an increase in glycemia, you necessarily have a glycation taking place in your blood. 语法解析
51:43
The consequence of glycation is neuropathy and poor microcirculation. So the more I believe right now with the state of the literature that you could probably like the best predictor of your health as you age is probably how much time you have spent from the day you're born to today with higher glycemia, which 语法解析
52:03
which sums up to how much glycation you have accumulated. And if you want to see today in your 40s, 50s, 60s, what's that state? Try to stand on one leg and see how long you can do it. It has affected your nerves. You have some level of subclinical neuropathy and you realize you can't stay balanced as you used to. 语法解析
52:23
And so to me, the discovery was just how often you get these massive peak in glycemia just by eating things that are like very trivial in our lives. So it made me change a lot of my habits. Not that I was a big sweet person. You know, I don't really consume a lot of sweets, but whatever I take, it allowed me to see that. So anyway, to me, it was a great discovery. 语法解析
52:48
Yeah, interesting. In terms of your dietary approach now, I'm actually curious to know what you tend to lean towards nutrition-wise. I've never really… 语法解析
53:01
paid a lot of attention to my nutrition other than eating very natural. So there's not a whole lot of processed stuff, you know, that I eat. I've been vegetarian since 87. So, so almost what, 40 years vegetarian. Um, and, um, 语法解析
53:20
And I'm totally fine. I have in the past few years with all this movement on meat and everything, I said, hey, why not? So I tried it a little bit and I don't do well on it. Like I do much better without meat. I do believe that this whole push to say meat protein is the best. I think it's just it's really just like. 语法解析
53:40
It's a marketing wave. It's not real. It's not true that meat protein is the best. Otherwise, I would say don't tell the cow because they think they're building their great meat. Don't tell them. They may stop eating grass. So you can totally – you're fine with vegetable protein. So anyway, I've been vegetarian since 1987. But I do eat a lot of – everything is natural. I don't touch processed meat. 语法解析
54:09
Yeah, no, incredible. And eggs as well. Awesome. Well, Christian, it was an absolute pleasure having you on the podcast again. I'm going to make sure that my listeners will be able to check out all the products linked in the video description and in the podcast show notes that you mentioned, the Mobilize, the STEM Regen, Signal, and the Release, different products there. And there'll also be a follow-up YouTube video coming out as well on the Mobilize that I've also covered in a YouTube video. But yeah, 语法解析
54:38
Christian, thank you so much for featuring on the podcast. My pleasure, Lucas. We'll do that again. 语法解析
Edit:2025.04.04